With hundreds of published titles, 3D GameStudio authoring suite for 2D, 3D realtime applications. It combines the C-Script programming language with a high-end 3D engine, a 2D engine, a physics engine, a level, terrain and model editor, etc...
W. Lavrijsen, and A. Dutta. Proceedings of the 6th Workshop on Python for High-Performance and Scientific Computing, page 27--35. Piscataway, NJ, USA, IEEE Press, (2016)