It has long been recognised that people with dementia and their family carers have palliative care needs equal to those of patients with cancer. However, a palliative approach to dementia care requires both the dementia and palliative care workforces to fully understand the needs of people with dementia and their families towards the end of life. This article describes the development of a ‘community of practice’ where healthcare professionals from dementia and palliative care services shared their practice and learned from each other in a safe and supportive environment.
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By characterising the full spectrum of temporal disease trajectories before dementia, this UK Biobank study aims to yield a global picture of precursor diseases to dementia and to provide detailed instructions for risk management and primary prevention of dementia. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This paper explores the impact that early-stage dementia has on everyday activities from the perspective of people living with dementia, their supporters and occupational therapy practitioners. Open access article - no login required.
This study investigates the experiences of 18 caregivers of people with dementia in Black Caribbean, Black African, and South Asian (Indian, Pakistani, and Bangladeshi) communities in England. Open access article - no login required.
Appropriate nutrition represents a potential strategy to mitigate dementia risk and could be recommended by clinicians as part of mid-life health checks and other health initiatives to reduce dementia prevalence. The purpose of this review is to provide a clinician-focused update on the current state of the knowledge on nutrition and dementia prevention.
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This meta-ethnographic review explains how people with early-onset dementia form their sense of identity. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study tested whether individuals who are most likely to need enhanced care later in the disease course can be identified at the point of diagnosis. Open access article - no login required.
Remote monitoring technologies show potential to help health professionals deliver preventative interventions which can avoid hospital admissions and allow patients to remain in a home setting.
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Using a case study approach, the authors describe the support available, spanning health and social care and third sector organisations. They discuss how this support can enable people with dementia and their carers to maintain wellbeing and cope with the impact of dementia.
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Hospital patients with behavioural and psychological symptoms of dementia (BPSD) are vulnerable to a range of adverse outcomes. Hospital-based Special Care Units (SCUs) are secure dementia-enabling environments providing specialised gerontological care. Due to a scarcity of research, their value remains unconfirmed.
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This is an important study that contributes to the evidence-base for a higher incidence rate of dementia among women compared to men, and a pooled higher risk of dementia among women. Other research has attributed increased levels of dementia among post-menopausal women to a potential detrimental neurological effect of lack of oestrogens (Rahman et al, 2020), while androgens are purported to have neuroprotective effects (Cai et al, 2020). However, the inconsistency of effect estimates seen by Gong et al. (2022) across cohorts suggests that, if a difference in dementia risk between men and women truly exists, this may not be fully explained by hormonal or biological factors.
This study explored the participant and caregiver experiences of CS-ADL (Cognitive Stimulation in Activities of Daily Living), an activities of daily living-focused group cognitive stimulation program for individuals with mild-to-moderate dementia. Open access article - no login required
This research examines how close family members consider themselves to contribute to the activities, routines and occupational identity of their elderly relatives with dementia who reside in long-term residential care, and the factors that support or challenge their involvement. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
When investigating health conditions as risk factors for dementia, it is necessary to consider how multiple health conditions cluster and whether the risk of dementia varies between different clusters. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
To explore nurses' experiences of providing support to South Asian (SA) people with dementia and their family carers and to identify barriers and enablers of good transcultural care.
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To explore the moral dimension of family experiences with being involved in the care of their loved one with dementia in the nursing home, using the care ethical framework of Tronto.
Open Access Article
Pharmacological treatments are very common to be used for alleviating neuropsychiatric symptoms (NPS) in dementia. However, decision on drug selection is still a matter of controversy.
Aims: To summarise the comparative efficacy and acceptability of currently available monotherapy drug regimens for reducing NPS in dementia.
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The purpose of this review was to explore the extent and nature of evidence concerning factors that influence the use of nonpharmacological interventions for community-dwelling seniors with mild-to-moderate dementia.
This paper aims to describe the outcomes of the use of the Quality Outcome Measure for individuals with dementia (QOMID) within a dementia pathway for people with Down’s syndrome (DS). The QOMID is a tool for clinicians to use with 17 outcome domains, each with descriptors for early, mid and late stage dementia, rated on a four point scale from rarely achieved for the person (1) to consistently and completely achieved for the person (4). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Challenges with communication are a feature of all types of dementia, so understanding how dementia affects communication and how to support people is important for all nurses. This article provides an overview of communication in dementia care. The authors draw on the literature on communication and dementia to present evidence-based, practical approaches for supporting person-centred communication with people with dementia.
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Much research has been conducted on the relationship between recovery orientation and people diagnosed with mental illnesses such as schizophrenia and mood disorders. A recovery-oriented approach by mental health professionals can reduce hospital stays and medical costs for people diagnosed with mental illness.
There are similarities and differences between recovery-oriented approaches for individuals diagnosed with dementia and those diagnosed with mental illness. This reflects the characteristics of irreversible dementia.
Although dementia courses at recovery colleges are increasing, dementia recovery is in its infancy and course content varies. The core of the recovery framework for individuals diagnosed with dementia is ‘Continue to be me’.
Recovery-oriented approaches and programmes have been developed by mental health workers for older adults, including those with dementia, but there are no outcome measures that reflect the characteristics of dementia care. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Early identification of older adults at higher risk of accumulating multimorbidity of specific pathophysiology and tailored interventions to prevent or delay the onset of such multimorbidity may help prevention of dementia. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The aim of this review was to chart what is known from the literature about the use of CS in improving ADL outcomes. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Dementia is a growing health concern. Persons with dementia experience higher levels of anxiety and depression, which correlates with poorer quality of life, disability and hospitalization. This is one of the few studies to use a longitudinal design to assess the impact of expressed emotion (EE) on well-being in dementia over time.
Music can stimulate the parts of the brain that regulate the pleasure receptors. Music is also neurologically unique in the way that it stimulates various parts of the brain at once. This suggests that in people with dementia if some parts of the brain are affected music can still reach other parts. Evidence suggests that music can have beneficial effects for people with dementia, such as reduction in agitation. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Anticholinergic burden is weakly associated with poorer cognition, but there is little evidence for associations with brain structure. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The findings from this study confirm the importance of age-related risperidone dose adjustments and argue strongly for therapeutic drug monitoring in the initial stages of treatment, to identify those at greatest risk of toxicity. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
A systematic review of the literature was completed to examine the needs of those who provide care to people with intellectual disability and dementia. The purpose of this paper was to develop an understanding of the complexities, challenges and support available to meet the needs of an ageing population. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
People under 65 with dementia can struggle to get a diagnosis and appropriate care, making greater awareness among nurses vital. Dementia is perceived as a condition of older people, but can also affect those in middle age or even younger. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
In an initiative to reduce stigma, an academic psychiatrist comes out of the dementia closet: describing his own experience of developing Alzheimer's disease, the accompanying memory problems, the restriction of some of his activities, emotional lability and his increasing reliance on others. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Older people with mental health needs and dementia often face difficulties with daily living and community participation, requiring the intervention of social care services. However, cognitive and emotional needs often mean that mainstream support is not appropriate. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Previous research on the association between proton pump inhibitors (PPIs) intake and the increased risk of dementia has shown discrepancies in conclusion. We aimed to provide updated evidence based on extensive bias assessments and quantitative sensitivity analyses. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The Dementia Questionnaire for People with Learning Disabilities (DLD) is one of the main screening and monitoring tools for dementia in people with Down’s syndrome (DS). As part of a quality improvement project to improve the care for people with DS and dementia in an intellectual disability service, the authors studied the screening and monitoring process by retrospectively investigating the use of DLD and exploring clinicians’ experience of using it. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The complex nature of end-of-life assessment of individuals diagnosed with dementia would benefit from a mixed methods approach that simultaneously assess the perception and response of nurses to standardised tools. Aim: To examine nursing professionals’ perceptions of the quality of dying among residents diagnosed with dementia using the Quality of Dying in Long-Term Care settings (QoD-LTC) questionnaire, and to identify consistencies and inconsistencies in their narratives.
Anti-dementia medications such as acetylcholinesterase inhibitors are an important part of the management pathway for dementia. However, there are limited data in New Zealand that have examined the rates and patterns of use of funded anti-dementia medication and how use differs with ethnicity, age and sex. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
In this review, the authors evaluate the evidence for efficacy and safety of nonpharmacological and pharmacological interventions for treating NPS, mostly based on published meta-analyses. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This review aimed to synthesize current evidence on family involvement in pain management for people living with dementia from the perceptions of family carers and health care professionals.
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Older adults with MCI who participated in the CrEAS program improved their neuropsychological outcomes and QoL and reduced their rate of cognitive deterioration.
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As the study showed, experiencing auditory hallucinations was linked to poorer well-being in dementia. This suggests that auditory hallucinations should be targeted by appropriate treatments when aiming to improve well-being in people living with the condition.
The Comprehensive Process Model of Group Engagement posits that personal factors (e.g., cognitive function), stimulus factors (e.g., group activity content, group size) and environmental factors (e.g., light, noise) impact the response to group activities. This paper reports the impact of environmental and group characteristics on engagement, mood, and sleepiness of persons with dementia attending group activities.. To read the full article, log in using your MPFT NHS OpenAthens details.
Worldwide, life expectancy and ageing‐related disorders as Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) are increasing, having a rising impact on patients’ quality of life and caregivers’ distress. Telemedicine offers many possibilities, such as remote diagnosing and monitoring patients.. To read the full article, log in using your MPFT NHS OpenAthens details.
To explore the complexities, circumstances, and range of services commissioned for people with dementia living at home.. To read the full article, log in using your MPFT NHS OpenAthens details.
To study the frequency of suicidal ideation and its association with clinical and neurobiological correlates among cognitively intact autosomal dominant Alzheimer's disease (ADAD) at‐risk individuals.. To read the full article, log in using your MPFT NHS OpenAthens details.
In the UK, an estimated 954 000 people have dementia. Lewy body dementia (LBD) can be difficult to diagnose and estimates of its prevalence in the UK range from 38 000–100 000 (Prince et al, 2014:14, 16; Table 4, 2019 estimates; NHS, 2019).
This article, the fourth in a series, explains about the pathophysiology and clinical features of LBD, how it is diagnosed, treated and managed. To read the full article, log in using your MPFT NHS OpenAthens details.
On 21 June 2019 the House of Commons Library published a briefing paper entitled Dementia: Policy, services and statistics, which reviews the policies, services and statistical evidence pertinent to people living with dementia in England (Powell and Baker, 2019).
This parliamentary briefing gives details of several campaigns and policies on dementia care in the UK, one of which is the campaign led by the Alzheimer's Society entitled ‘Fix Dementia Care’. This campaign calls for the state to play a larger role in underwriting the costs of dementia care. To read the full article, log in using your MPFT NHS OpenAthens details.
A study investigating the link between gum disease bacteria and Alzheimer's disease has found compelling correlational evidence, with implications for treatment. To read the full article, log in using your MPFT NHS OpenAthens details.
A major contributor to dementia in Parkinson disease (PD) is degeneration of the cholinergic basal forebrain. This study determined whether cholinergic nucleus 4 (Ch4) density is associated with cognition in early and more advanced PD.. To read the full article, log in using your NHS OpenAthens details.
Free access. Dementia is a common, debilitating feature of late Parkinson’s disease (PD). PD dementia (PDD) is associated with α-synuclein propagation, but coexistent Alzheimer’s disease (AD) pathology may coexist. Other pathologies (cerebrovascular, transactive response DNA-binding protein 43 (TDP-43)) may also influence cognition. We aimed to describe the neuropathology underlying dementia in PD.
Open access. Traumatic brain injury (TBI) leads to increased rates of dementia, including Alzheimer’s disease. The mechanisms by which trauma can trigger neurodegeneration are increasingly understood. For example, diffuse axonal injury is implicated in disrupting microtubule function, providing the potential context for pathologies of tau and amyloid to develop. The neuropathology of post-traumatic dementias is increasingly well characterised, with recent work focusing on chronic traumatic encephalopathy (CTE). However, clinical diagnosis of post-traumatic dementia is problematic. It is often difficult to disentangle the direct effects of TBI from those produced by progressive neurodegeneration or other post-traumatic sequelae such as psychiatric impairment. CTE can only be confidently identified at postmortem and patients are often confused and anxious about the most likely cause of their post-traumatic problems.
Multimodal MRI-based classification may aid early frontotemporal dementia (FTD) diagnosis. Recently, presymptomatic FTD mutation carriers, who have a high risk of developing FTD, were separated beyond chance level from controls using MRI-based classification. However, it is currently unknown how these scores from classification models progress as mutation carriers approach symptom onset. In this longitudinal study, we investigated multimodal MRI-based classification scores between presymptomatic FTD mutation carriers and controls. Furthermore, we contrasted carriers that converted during follow-up (‘converters’) and non-converting carriers (‘non-converters’).. To read the full article, log in using your NHS OpenAthens details.
Nurse specialists have helped create a dementia-friendly X-ray room with woodland imagery and music tailored to each patient. To read the full article, log in using your MPFT NHS OpenAthens details.
A new dementia app could prove a vital tool in supporting patients and families from black and minority ethnic (BME) communities, according to a leading nurse. To read the full article, log in using your MPFT NHS OpenAthens details.
Older lesbian, gay, bisexual, trans, queer and others (LGBTQ+) people living with dementia have specific needs related to their sexual orientation and identity that should be addressed to maintain their personhood. They may face challenges in health and social care settings, such as heteronormativity and lack of awareness of older LGBTQ+ needs. Service provision for older LGBTQ+ people with dementia is lacking. Healthcare professionals’ attitudes towards older LGBTQ+ people with dementia are often poor and there is a clear need for better training, while increased knowledge and awareness would help to challenge the concept of heteronormativity. To read the full article, log in using your MPFT NHS OpenAthens details.
While these initial results are interesting for researchers, this treatment is still in the experimental stages. Further study in more people is needed to ensure that it causes no long-term harm and to get a better idea of what impact it could have on clinical outcomes in a wider setting.
Hence we're still some way off from knowing whether this really is a breakthrough in AD treatment.
To examine the association between hearing aids (HAs) and time to diagnosis of Alzheimer disease (AD) or dementia, anxiety or depression, and injurious falls among adults, aged 66 years and older, within 3 years of hearing loss (HL) diagnosis.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Half of nursing home residents (NHR) suffer from dementia. End-of-life hospitalizations are often burdensome in residents with dementia. A systematic review was conducted to study the occurrence of hospitalizations at the end of life in NHR with dementia and to compare these figures to NHR without dementia. Open Access Article
Nurses can offer understanding, assessment and a plan to manage incontinence. Health and social care staff have a vital role in managing continence for people in a variety of settings. To read the full article, log in using your MPFT NHS OpenAthens details.
The aim of the current study is to describe the extended design of the Living Arrangements for people with Dementia (LAD)‐study.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Dementia is the most common neurological disease in older adults; headaches, including migraines, are the most common neurological disorder across all ages. The objective of this study was to explore the relationship between migraines and dementia, including Alzheimer's disease (AD) and vascular dementia (VaD).. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
To investigate the presence of cerebral amyloidopathy and its associations with performances on neurocognitive tests and clinical features in depressed elders with mild cognitive impairment (MCI).. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Sexual disinhibition in dementia is correlated with multiple negative care recipient and caregiver outcomes but remains largely overlooked in the literature. Its prevalence is not well understood, with studies reporting between 1.8% and 25% presence of sexual disinhibition in dementia samples. One reason for the variability in the reported presence of sexual disinhibition may be lack of standardized methods for assessment. Several widely used measures for neuropsychiatric symptoms do not include items to assess sexual disinhibition. When measures do include sexual disinhibition, it is not addressed in a consistent manner. Inconsistency in how questions about sexual disinhibition are phrased is problematic, given that recent work shows it can differentially influence endorsement.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Although many home nations fans might find sitting through this year’s rugby world cup matches a little too nerve-racking at times, the NHS says watching the sport can actually be good for your mental health and wellbeing.
NHS hospitals are going back to the future to help patients with dementia by decorating their wards, rooms and corridors in 1940s and 1950s style – creating a calming, familiar environment which can help jog memories, reduce anxiety and distress.
Social isolation can be problematic for people with dementia; understanding what makes communication meaningful may reduce such risk.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
The objectives of this study are to explore the feasibility of a multicomponent intervention programme and to evaluate its impacts on behavioural and psychological symptoms of dementia (BPSD) and psychological health of caregivers.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Quality of life is important especially in incurable illness. In dementia, we often need proxy reports of quality of life, but we know little about how individuals make their judgements. In care homes, proxies may be staff providing care or relatives, but staff rate quality of life differently to family. To our knowledge, no one has explored this qualitatively, so we used qualitative interviews to explore why staff and family think differently about quality of life.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Free access. Differentiating normal cognition, mild cognitive impairment (MCI), and dementia is important, as these conditions differ in terms of their prognosis and treatment. Existing short cognitive screening tests vary widely in their accuracy, sensitivity, and specificity at detecting MCI and dementia. The Quick Mild Cognitive Impairment Screen (QMCI) was developed in 2012 as a fast and accurate “MCI specific” screening test. The aim of the current study was to conduct a literature review to compare the accuracy, sensitivity, and specificity of the QMCI at differentiating normal cognition, MCI, and dementia to existing short cognitive screening tests at their optimal cut‐off scores.
Cognitive impairment is common in patients with chronic kidney disease (CKD), possibly leading to poor outcomes. However, the correlation between brain structural abnormalities and cognitive impairment remains unclear. The aim of this study was to investigate the impairment of specific cognitive domains and their association with brain structural abnormalities.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Relatively few APOE ε4+ carriers survive to old age (age 80+) without cognitive impairment (CI); thus, little is known about distinguishing characteristics of resilient APOE ε4+ carriers. Herein, we describe the sociodemographic characteristics of a large sample of resilient APOE ε4+ women from the Women's Health Initiative Memory Study (WHIMS) and compare them to noncarriers and APOE ε4+ women who developed CI before age 80.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
To identify subtypes of neuropsychiatric symptom (NPS) course among cognitively normal individuals and to assess the association between these subtypes and hazard of later mild cognitive impairment (MCI) or dementia diagnosis.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Memory complaints are a common concern for older adults and may co‐occur with anxiety symptoms. Although both memory complaints and anxiety are associated with heightened cognitive decline risk, little is known about how these symptoms develop over time. The purpose of this study was to examine the differential concurrent and longitudinal relationships among anxiety symptoms and two types of memory complaints in cognitively intact older adults.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
To explore and understand carer participation in support groups when caring for a person with dementia who lives at home. . To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Anxiety and depression are common and deleterious comorbidities in people living with dementia (PLWD). Cognitive behavioural therapy (CBT) is one of the few promising treatments; however, it is unclear whether PLWD have the necessary prerequisites to engage in this. Having an understanding of cognitive mediation, that a thought mediates the relationship between an antecedent event and its emotional consequence, is key for engaging with CBT and is also a critical component of emotion regulation. There are no measures of this construct validated for PLWD. This study aims to adapt and validate an existing measure for this population. A secondary aim is to assess its applicability in older adults (OA) without a recognised neurocognitive impairment.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Free access. Cognitive impairment is underdiagnosed in primary care. Understanding factors that precipitate memory‐related discussion could inform strategies to improve diagnosis and counseling. We assessed whether: 1) having a cognitive impairment or dementia diagnosis, 2) ratings of cognition by clinicians, or 3) ratings of cognition by family companions were associated with memory‐related discussion during primary care visits.
Free access. This study was conducted to estimate prevalence rates and factors associated with depressive symptoms indexed by the Centre for Epidemiological Studies‐Depression (CES‐D‐10) score in a large sample of community‐dwelling healthy older adults from Australia and the United States. Convergent and divergent validity of the CES‐D‐10 were also examined.
Free access. This study aimed to examine the association of loneliness and social isolation on cognition over a 3‐year follow‐up period in middle‐ and older‐aged adults.
Open access. Previous studies have identified several subgroups (ie, latent trajectories) with distinct disease progression among people with dementia. However, the methods and results were not always consistent. This study aims to perform a coordinated analysis of latent trajectories of cognitive and functional progression in dementia across two datasets.
Psychosis of Alzheimer's disease (AD) may represent a distinct disease phenotype, however neuropsychological profile and neural basis linked to this phenotype have not yet been clarified. In this study, we aimed at detecting whether impairment in specific cognitive domains predicts the onset of psychosis in AD patients and what grey matter alterations, their location and the rate of atrophy are associated with psychosis of AD. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
The aim of this study was to develop and validate a new brief and accurate case‐finding instrument for dementia and cognitive impairment. Previous research indicates that combining cognitive tests with informant and/or patient report may improve accuracy in dementia case‐finding. The Brief Assessment of Impaired Cognition (BASIC) integrates these three sources of information.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Dementia affects a person’s ability and desire to eat and drink to meet their nutritional requirements. This article identifies problems associated with nutritional status in people living with dementia and outlines the effectiveness of interventions to counteract the negative effects on nutritional status. To read the full article, log in using your MPFT NHS OpenAthens details.
In the UK, an estimated 954 000 people have dementia. Alzheimer's-type dementia (AD) is the most common type of dementia and affects around 591 480 people (Prince et al, 2014). This article, the second in a series, explains about the pathophysiology and clinical features of AD, how it is diagnosed and the medication used to treat it. To read the full article, log in using your MPFT NHS OpenAthens details.
As the UK's older population continues to rise, the more likely it is for practice nurses to encounter patients living with Alzheimer's and frailty. Kirsty Smith and Sophie Wallington explore the definitions and models of frailty available in medical literature. To read the full article, log in using your MPFT NHS OpenAthens details.
Implications for practice and research:
>Older adults living with Alzheimer’s disease (AD) respond best to patient-centred care that values and affirms personhood and maintains the ‘self’.
>Research to examine perceptions and attitudes of professional care staff towards AD in older adults may provide insight into pre-existing quality of life (QOL) biases. To read the full article, log in using your NHS OpenAthens details.
Editorial comment. The study by Licher et al. in this issue (1) describes a basic and an extended dementia risk model in predicting 10-year risk for all-cause dementia. The basic risk model includes variables that could be easily collected in a primary care setting, and the extended model evaluates the added value of APOE4 status, quantitative MRI imaging characteristics, and cognitive test scores in predicting risk for all-cause dementia.. Login at top right hand side of page using your MPFT NHS OpenAthens for full text.
Open access. Frontotemporal dementia (FTD) is a pathologically heterogeneous neurodegenerative disorder associated usually with tau or TDP-43 pathology, although some phenotypes such as logopenic variant primary progressive aphasia are more commonly associated with Alzheimer’s disease pathology. Currently, there are no biomarkers able to diagnose the underlying pathology during life. In this study, we aimed to investigate the potential of novel tau species within cerebrospinal fluid (CSF) as biomarkers for tau pathology in FTD.
Although chronic periodontitis has been associated with Alzheimer's disease, the effect of chronic periodontitis on vascular dementia as well as the role of lifestyle behaviors such as smoking, alcohol consumption, and physical activity in this association are still unclear.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Reducing potentially preventable hospitalization (PPH) among older adults with dementia is a goal of Healthy People 2020, yet no tools specifically identify patients with dementia at highest risk. The objective was to develop a risk prediction model to identify older adults with dementia at high imminent risk of PPH.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Editorial . To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Population‐based incidence estimates of dementia and Alzheimer disease (AD) provide important information for public health policy and resource allocation. We conducted a meta‐analysis of published studies that reported age‐specific incidence rates of dementia and AD to determine whether dementia and AD incidence rates are changing over time.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
F. Molnar, B. Hutton, and D. Fergusson. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 179 (8):
751-3(October 2008)4563<br/>PUBM: Print; JID: 9711805; ppublish;<br/>Dades censurades; LOCF; Bias.