Patients with cancer-related anaemia generally have a poor prognosis. Evidence suggests that an effective erythropoietic protein (epoetin)-mediated haemoglobin (Hb) response provides marked improvement in quality of life (QoL)...the use of an agent which
Aging may be an intrinsic factor in the development of anemia, possibly through the age-related dysregulation of certain proinflammatory cytokines such as interleukin-6 (IL-6)...Increased IL-6 and other proinflammatory cytokines directly inhibit erythropo
Mind-boggling networks of cytokines and transcription factors have been invoked to explain the anemia of inflammation. Does it really have to be so complicated? Elevated hepcidin; defensive sequestering of serum ferritin (iron); direct cytokine disruption