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1Worldwide distribution of human Y-chromosome haplotypes - PubMed
We surveyed several human populations worldwide with three PCR-based polymorphisms located in the human Y chromosome: the alphoid heteroduplex [alpha(h)] polymorphic system, the DYS19 microsatellite locus, and a polymorphic Alu insertion (YAP). By typing with the former two polymorphisms [alpha(h) a …
12 months ago by @hcariou
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1Inferring the evolutionary histories of the Adh and Adh-dup loci in Drosophila melanogaster from patterns of polymorphism and divergence.
M. Kreitman, and R. Hudson. 127 (3): 565--582 (1991)
7 years ago by @peter.ralph
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Adh
Drosophila
dip_in_diversity
haplotypes
hitchhiking
selective_sweep
AdhDrosophiladip_in_diversityhaplotypeshitchhikingselective_sweep
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1Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone
L. Wang, K. Luzynski, J. Pool, V. Janoušek, P. Dufková, M. Vyskočilová, K. Teeter, M. Nachman, P. Munclinger, M. Macholán and 2 other author(s). Mol Ecol, 20 (14): 2985-3000 (July 2011)
9 years ago by @peter.ralph
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LD
Mus
ancestral_disequilibrium
haplotypes
house_mouse
hybrid_zones
mouse_hybrid_zone
LDMusancestral_disequilibriumhaplotypeshouse_mousehybrid_zonesmouse_hybrid_zone
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1Identification of polymorphic inversions from genotypes
A. Cáceres, S. Sindi, B. Raphael, M. Cáceres, and J. González. BMC Bioinformatics, (2012)
9 years ago by @peter.ralph
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haplotypes
human_genome
inversions
methods
structural_variation
haplotypeshuman_genomeinversionsmethodsstructural_variation
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1Identification and frequency estimation of inversion polymorphisms from haplotype data
S. Sindi, and B. Raphael. J Comput Biol, 17 (3): 517-531 (March 2010)
9 years ago by @peter.ralph
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haplotypes
human_genome
inversions
structural_variation
haplotypeshuman_genomeinversionsstructural_variation
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1Parente2: a fast and accurate method for detecting identity by descent
J. Rodriguez, S. Bercovici, L. Huang, R. Frostig, and S. Batzoglou. Genome Res, (October 2014)
10 years ago by @peter.ralph
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IBD
haplotypes
methods
software
IBDhaplotypesmethodssoftware
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1A breast cancer risk haplotype in the caspase-8 gene
N. Shephard, R. Abo, S. Rigas, B. Frank, W. Lin, I. Brock, A. Shippen, S. Balasubramanian, Reed, Malcolm Walter Ronald, C. Bartram and 8 other author(s). Cancer research, 69 (7): 2724–2728 (2009)
10 years ago by @drtester
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Breast_Neoplasms/enzymology/genetics
Case-Control_Studies
Caspase_8/genetics
Chromosome_Mapping
Female
Genetic_Predisposition_to_Disease
Haplotypes
Humans
Polymorphism,_Single_Nucleotide
Breast_Neoplasms/enzymology/geneticsCase-Control_StudiesCaspase_8/geneticsChromosome_MappingFemaleGenetic_Predisposition_to_DiseaseHaplotypesHumansPolymorphism,_Single_Nucleotide
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1No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis
O. Jaen, E. Petit-Teixeira, H. Kirsten, P. Ahnert, L. Semerano, C. Pierlot, F. Cornelis, M. Boissier, and G. Falgarone. Arthritis research & therapy, 11 (1): R5 (2009)
10 years ago by @drtester
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Adult
Arthritis,_Rheumatoid/genetics
Female
Genetic_Predisposition_to_Disease
Genotype
Haplotypes
Humans
Linkage_Disequilibrium
Male
Polymerase_Chain_Reaction
Polymorphism,_Restriction_Fragment_Length
Polymorphism,_Single_Nucleotide
Toll-Like_Receptors/genetics
AdultArthritis,_Rheumatoid/geneticsFemaleGenetic_Predisposition_to_DiseaseGenotypeHaplotypesHumansLinkage_DisequilibriumMalePolymerase_Chain_ReactionPolymorphism,_Restriction_Fragment_LengthPolymorphism,_Single_NucleotideToll-Like_Receptors/genetics
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1Double heterozygosity for mutations in BRCA1 and BRCA2 in German breast cancer patients: implications on test strategies and clinical management
S. Heidemann, C. Fischer, C. Engel, B. Fischer, L. Harder, B. Schlegelberger, D. Niederacher, T. Goecke, S. Doelken, N. Dikow and 4 other author(s). Breast cancer research and treatment, 134 (3): 1229–1239 (2012)
10 years ago by @drtester
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Adult
Age_of_Onset
Aged
Breast_Neoplasms/epidemiology/genetics
Ethnic_Groups/genetics
Family
Female
Genes,_BRCA1
Genes,_BRCA2
Genetic_Predisposition_to_Disease
Haplotypes
Heterozygote
Humans
Middle_Aged
Mutation
Pedigree
Phenotype
Risk_Factors
AdultAge_of_OnsetAgedBreast_Neoplasms/epidemiology/geneticsEthnic_Groups/geneticsFamilyFemaleGenes,_BRCA1Genes,_BRCA2Genetic_Predisposition_to_DiseaseHaplotypesHeterozygoteHumansMiddle_AgedMutationPedigreePhenotypeRisk_Factors
(0)
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1Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection
J. Fischer, S. Böhm, M. Scholz, T. Müller, H. Witt, J. George, C. Sarrazin, S. Susser, E. Schott, V. Suppiah and 7 other author(s). Hepatology (Baltimore, Md.), 55 (6): 1700–1710 (2012)
10 years ago by @drtester
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Adult
Cohort_Studies
Drug_Therapy,_Combination
Female
Genotype
Haplotypes
Hepatitis_C,_Chronic/drug_therapy/genetics/virology
Humans
Interleukins/genetics
Male
Middle_Aged
Polymorphism,_Single_Nucleotide
Treatment_Outcome
AdultCohort_StudiesDrug_Therapy,_CombinationFemaleGenotypeHaplotypesHepatitis_C,_Chronic/drug_therapy/genetics/virologyHumansInterleukins/geneticsMaleMiddle_AgedPolymorphism,_Single_NucleotideTreatment_Outcome
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1Genome Patterns of Selection and Introgression of Haplotypes in Natural Populations of the House Mouse (Mus musculus)
F. Staubach, A. Lorenc, P. Messer, K. Tang, D. Petrov, and D. Tautz. PLoS Genet, 8 (8): e1002891 (August 2012)
12 years ago by @peter.ralph
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Mus
clines
haplotypes
hybrid_filter
hybrid_zone
introgression
population_genomics
selection
Musclineshaplotypeshybrid_filterhybrid_zoneintrogressionpopulation_genomicsselection
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1Reconstructing ancestral haplotypes with a dictionary model
K. Ayers, C. Sabatti, and K. Lange. J. Comput. Biol., (April 2006)
14 years ago by @peter.ralph
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haplotypes
linkage
haplotypeslinkage
(0)
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1A fine-scale linkage-disequilibrium measure based on length of haplotype sharing
Y. Wang, L. Zhao, and S. Dudoit. The American Journal of Human Genetics, 78 (4): 615--628 (2006)
14 years ago by @peter.ralph
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haplotype_length
haplotypes
linkage
haplotype_lengthhaplotypeslinkage
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1A natural history of FUT2 polymorphism in humans
A. Ferrer-Admetlla, M. Sikora, H. Laayouni, A. Esteve, F. Roubinet, A. Blancher, F. Calafell, J. Bertranpetit, and F. Casals. Mol. Biol. Evol., (September 2009)
14 years ago by @peter.ralph
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FUT2
balancing_selection
geographic_variation
haplotypes
parallel_adaptation
FUT2balancing_selectiongeographic_variationhaplotypesparallel_adaptation
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1A worldwide survey of haplotype variation and linkage disequilibrium in the human genome
D. Conrad, M. Jakobsson, G. Coop, X. Wen, J. Wall, N. Rosenberg, and J. Pritchard. Nat Genet, 38 (11): 1251-1260 (November 2006)
14 years ago by @peter.ralph
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haplotype_visualization
haplotypes
linkage
spatial_structure
survey
haplotype_visualizationhaplotypeslinkagespatial_structuresurvey
(0)
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2Genetic signatures of strong recent positive selection at the lactase gene
T. Bersaglieri, P. Sabeti, N. Patterson, T. Vanderploeg, S. Schaffner, J. Drake, M. Rhodes, D. Reich, and J. Hirschhorn. Am J Hum Genet, 74 (6): 1111-1120 (June 2004)
14 years ago by @peter.ralph
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haplotypes
lactase
selection
haplotypeslactaseselection
(0)
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1Haplotype allelic classes for detecting ongoing positive selection
J. Hussin, P. Nadeau, J. Lefebvre, and D. Labuda. BMC Bioinformatics, (2010)
14 years ago by @peter.ralph
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haplotypes
lactase
selection
haplotypeslactaseselection
(0)
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2Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100
B. Schneider, M. Wang, M. Radovich, G. Sledge, S. Badve, A. Thor, D. Flockhart, B. Hancock, N. Davidson, J. Gralow and 6 other author(s). J.Clin.Oncol., 26 (28): 4672-4678 (2008)
15 years ago by @kanefendt
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&
A
Antibodies
Antineoplastic
Breast
Chemotherapy
Combined
Dna
Endothelial
Factor
Female
Genotype
Growth
Haplotypes
Hazards
Humans
Hypertension
Models
Monoclonal
Neoplasms
Nonparametric
Nucleotide
Paclitaxel
Polymorphism
Proportional
Protocols
Rate
Receptor-2
Research
Retrospective
Single
Statistics
Studies
Survival
Vascular
administration
dosage
drug
genetics
methods
pathology
therapeutic
therapy
toxicity
use
&AAntibodiesAntineoplasticBreastChemotherapyCombinedDnaEndothelialFactorFemaleGenotypeGrowthHaplotypesHazardsHumansHypertensionModelsMonoclonalNeoplasmsNonparametricNucleotidePaclitaxelPolymorphismProportionalProtocolsRateReceptor-2ResearchRetrospectiveSingleStatisticsStudiesSurvivalVascularadministrationdosagedruggeneticsmethodspathologytherapeutictherapytoxicityuse
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1Worldwide distribution of human Y-chromosome haplotypes - PubMed

publications (hide)17
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1Inferring the evolutionary histories of the Adh and Adh-dup loci in Drosophila melanogaster from patterns of polymorphism and divergence.

1Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone

1Identification of polymorphic inversions from genotypes

1Identification and frequency estimation of inversion polymorphisms from haplotype data

1Parente2: a fast and accurate method for detecting identity by descent

1A breast cancer risk haplotype in the caspase-8 gene

1No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis

1Double heterozygosity for mutations in BRCA1 and BRCA2 in German breast cancer patients: implications on test strategies and clinical management

1Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection

1Genome Patterns of Selection and Introgression of Haplotypes in Natural Populations of the House Mouse (Mus musculus)

1Reconstructing ancestral haplotypes with a dictionary model

1A fine-scale linkage-disequilibrium measure based on length of haplotype sharing

1A natural history of FUT2 polymorphism in humans

1A worldwide survey of haplotype variation and linkage disequilibrium in the human genome

2Genetic signatures of strong recent positive selection at the lactase gene

1Haplotype allelic classes for detecting ongoing positive selection

2Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100

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