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Deep brain stimulation for Parkinson’s disease: defining the optimal location within the subthalamic nucleus | Journal of Neurology, Neurosurgery & Psychiatry


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Individual motor improvement after deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson’s disease (PD) varies considerably. Stereotactic targeting of the dorsolateral sensorimotor part of the STN is considered paramount for maximising effectiveness, but studies employing the midcommissural point (MCP) as anatomical reference failed to show correlation between DBS location and motor improvement. The medial border of the STN as reference may provide better insight in the relationship between DBS location and clinical outcome.. To read the full article, log in using your NHS OpenAthens details.

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