The authors highlight the important role that loneliness and social isolation can play in developing frailty in old age. This is particularly important at a time when COVID-19 restrictions have been in place for a prolonged period of time over the past 18 months in the UK/ in the four nations, and across the globe. The authors rightly refer to the negative impacts that being restricted to one’s own home, or being told to shield, can have on feelings of loneliness and social isolation, which may cause difficulties in terms of frailty for older adults in the long-term