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Genome-wide association study identified six loci associated with adverse drug reactions to aripiprazole in schizophrenia patients | Schizophrenia


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Aripiprazole is recommended for routine use in schizophrenia patients. However, the biological mechanism for the adverse drug reactions (ADRs) among schizophrenia patients with the antipsychotic drug aripiprazole is far from clear. To explore the potential genetic factors that may cause movement-related adverse antipsychotic effects in patients, we conducted an association analysis between movement-related ADRs and SNPs in schizophrenia patients receiving aripiprazole monotherapy. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.

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