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Too late to be included in this review, NICE Guideline Depression in adults, was issued in 2022 with more complete tapering information, including an exponential taper to be adjusted to the tolerance of the individual patient. It advised clinicians “slowly reduce the dose to zero in a step-wise fashion, at each step prescribing a proportion of the previous dose” and “consider using smaller reductions”. While this is still not very specific, it is a significant improvement over the guidance reviewed in this paper.

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