This report sets out the findings of ethnographic research project which conducted indepth-interviews with 10 people living with multiple long-term health conditions (MLTCs). The research aimed to better understand the growing challenges facing those living with MLTCs and their interactions with the health and social care professionals that support them. Individuals describe their own perceptions of their quality of life, often describing what they have ‘lost’ over time, such as a loss of mobility, social connectedness,and a decrease in mental wellbeing. They also explain that by adapting and developing coping strategies, they could regain some agency and make decisions about their conditions and their lives. Maintaining meaningful relationships with family and friends, and developing strong relationships with health and social care professionals were also found to be helpful. You can request a copy of this article by replying to this email. Please be clear which article you are requesting.