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Cochrane Clinical Answers - Fulltext - How does topiramate compare with carbamazepine as monotherapy for people with newly diagnosed epilepsy?


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Topiramate and carbamazepine appear to be similarly effective in inducing seizure freedom, although analyses including only people with focal (partial)-onset seizures revealed that treatment with carbamazepine resulted in a higher rate of seizure freedom at 12 months and a lower rate of treatment withdrawal.

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