Chronic pain can have significant physical, psychological and social effects on a person’s life, as well as on their families and friends. However, it is often not well-recognised or understood, which can lead to further harm. To read the full article, log in using your MPFT NHS OpenAthens details.
To search out whether or not years of education is causally related to rheumatoid arthritis (RA).. To read the full article, log in using your NHS OpenAthens details.
Conclusions
A majority of women with FM and CWP appear to have a positive course of pain over time, which should be communicated to these patients in health care. Reducing stress levels might contribute to better chances of improvement over time.
Objective To evaluate clinical outcomes in patients who changed treatment from adalimumab to baricitinib, an oral Janus kinase (JAK)1/JAK2 inhibitor, during a phase III programme. To read the full article, log in using your NHS OpenAthens details.
Conclusions
Foot orthoses made of soft materials may lead to more (immediate) forefoot plantar pressure reduction compared to foot orthoses constructed of semi-rigid materials. Definitive high quality RCTs, with adequate sample sizes and long-term follow-up, are needed to investigate the comparative (cost-) effectiveness of different kinds of foot orthoses for the treatment of foot problems related to rheumatoid arthritis.
This article highlights practical considerations in the initiation, switching and discontinuation of biologics in the management of JIA. To read the full article, log in using your NHS OpenAthens details.
Aim: To summarise the effectiveness of organisational interventions on appropriate opioid prescribing for non-cancer pain upon hospital discharge. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Rheumatoid arthritis (RA) and osteoarthritis (OA) both are chronic diseases affecting joints. There is a hypothesis that suppression of immune response vs collagen could be a therapeutic approach in RA and OA. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Systemic lupus erythematosus (SLE) with severe coronary artery disease (CAD) is associated with increased mortality. This study aimed to assess the characteristics and risk factors of severe CAD in SLE. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Since 2010, biological disease-modifying antirheumatic drugs (bDMARDs) have been the dominant mode of treatment for rheumatoid arthritis (RA). However, the safety of DMARDs, such as tumor necrosis factor inhibitors (TNFis) and Janus kinase inhibitors (JAKis), in treating patients with RA is a concern. We compared the safety outcomes of JAKis and TNFis in RA patients in clinical settings. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This work aims to evaluate the peripheral nerves and muscle involvement after COVID-19 infection, in addition to studying the prevalence rate and risk factors of their affection. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The objective of this systematic review was to evaluate the efficacy of immunosuppressive therapy in patients with connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) and to further assess whether response differs between CTD subtypes and clinical features. To read the full article, choose “Institutional Login” and search for “Midlands Partnership”.
Secukinumab, the first IL-17A inhibitor, is widely used to treat immune diseases, including plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. Here, we aimed to explore the clinical characteristics, outcomes, and time to onset of the four main toxicities of secukinumab, using post-marketing data. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Schools play a key role in adolescents' experiences with managing ME/CFS. However, little is known about the experiences of adolescents with ME/CFS (and their families) in schools. This paper is an incidental qualitative study, which combines data from two independent ME/CFS studies: study 1 researched ethnic minority adolescents with ME/CFS; study 2 explored Acceptance and Commitment Therapy for adolescents with ME/CFS who had not recovered after one year. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Systemic lupus erythematosus (SLE) is a heterogeneous systemic autoimmune diseases (AIDs) with many pathogenic factors, ranging from genetic to epigenetic to environmental. In this article, we provide a report of a case of SLE onset following HPV vaccination and a review of 11 similar cases. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Rheumatoid arthritis (RA) is a systemic autoimmune polyarticular disease. Despite being commonly affected in RA, the ankle and foot do not receive much attention, particularly in early disease. The precise diagnosis of their involvement and its impact on health is a clinical challenge that requires accurate assessment. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The study demonstrates the potential of integrating traditional biomarkers with unsupervised clustering algorithms in understanding the heterogeneity of AoSD. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This guideline updates recommendations for prevention and treatment of glucocorticoid-induced osteoporosis (GIOP) for patients with rheumatic or nonrheumatic conditions receiving >3 months treatment with glucocorticoids (GCs) ≥2.5 mg daily. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The current study aims to assess the efficacy of baricitinib in treating SLE patients. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This population-based study investigated the incidence and factors associated with mental illness among patients with rheumatoid arthritis receiving b/tsDMARDs. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.