To obtain the perspective of individuals with systemic lupus erythematosus (SLE) regarding the role of poverty, neighborhood, and chronic stress in SLE outcomes. To read the full article, log in using your NHS OpenAthens details.
Cervical spine involvement in patients with rheumatoid arthritis (RA) can cause pain and disability, with a variety of neurologic signs and symptoms. To read the full article, log in using your MPFT NHS OpenAthens details.
Rheumatoid arthritis is an autoimmune disease that causes joint inflammation. It affects around 400,000 people in the UK and 1 million adults in the USA. Given the appropriate treatment, many can have relatively few symptoms. It is therefore important to understand what it is like to live with rheumatoid arthritis and gain insight into peoples’ decisions about utilising healthcare. The aims of this study were: (1) to bring together qualitative evidence syntheses that explore patients’ experience of living with rheumatoid arthritis and (2) develop a conceptual understanding of what it is like to live with rheumatoid arthritis. Open Access
Frequent monitoring of early rheumatoid arthritis (RA) patients is required for achieving good outcomes. We studied the influence of text message (SMS) enhanced monitoring on early RA outcomes. To read the full article, log in using your NHS OpenAthens details.
We investigated the impact and timing of smoking cessation on developing rheumatoid arthritis (RA) and serologic phenotypes. To read the full article, log in using your NHS OpenAthens details.
We evaluated the discriminant capacity of the Lupus Low Disease Activity State (LLDAS) in post-hoc analysis of data from the BLISS-52 and BLISS-76 trials of belimumab in systemic lupus erythematosus (SLE). To read the full article, log in using your NHS OpenAthens details.
Rheumatoid arthritis (RA) has been associated with a relative expansion of faecal Prevotellaceae. To determine the microbiome composition and prevalence of Prevotella spp. in a group of individuals at increased risk for RA, but prior to the development of the disease.To read the full article, log in using your NHS OpenAthens details.
This open‐label study further supports the evidence that patients with SMX respond both objectively and subjectively to IVIG therapy. Biologic studies suggest a role for T lymphocytes in the pathogenesis of the disease, and reveal the potential significance of TGFβ and interferon pathways. To read the full article, log in using your MPFT NHS OpenAthens details.
There are common, potentially modifiable, patient‐ and rheumatologist‐reported barriers to achieving RA disease control, including perceived medication risk aversion, suboptimal treatment adherence, and suboptimal patient‐physician communication regarding the benefits of tight control of disease activity in RA. Addressing these obstacles may improve adherence to goal‐directed RA care. To read the full article, log in using your MPFT NHS OpenAthens details.
Objective To evaluate clinical outcomes in patients who changed treatment from adalimumab to baricitinib, an oral Janus kinase (JAK)1/JAK2 inhibitor, during a phase III programme. To read the full article, log in using your NHS OpenAthens details.
Conclusions
A majority of women with FM and CWP appear to have a positive course of pain over time, which should be communicated to these patients in health care. Reducing stress levels might contribute to better chances of improvement over time.
Conclusions
Foot orthoses made of soft materials may lead to more (immediate) forefoot plantar pressure reduction compared to foot orthoses constructed of semi-rigid materials. Definitive high quality RCTs, with adequate sample sizes and long-term follow-up, are needed to investigate the comparative (cost-) effectiveness of different kinds of foot orthoses for the treatment of foot problems related to rheumatoid arthritis.
This study aims 1) to explore individual differences in women with chronic pain (CP) in regard to pain intensity, functional impairment, cognitive fusion and depressive symptoms, and 2) to longitudinally test whether cognitive fusion is a significant predictor of depression symptoms, while controlling for pain intensity and functional impairment, over a 12‐month period.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
To search out whether or not years of education is causally related to rheumatoid arthritis (RA).. To read the full article, log in using your NHS OpenAthens details.
Tender joint count (TJC) is included in Composite Disease Activity Scores (CDAS) (DAS28/CDAI/SDAI). The impact of having predominantly tender joints was explored by use of the Tender‐Swollen Joint count Difference (TSJD). Ultrasound (US) provides a measure of joint inflammation. The present study aimed to explore the cross‐sectional and longitudinal associations between TSJD and a spectrum of outcome measures including US scores in patients with established rheumatoid arthritis (RA) during follow‐up on bDMARD treatment. To read the full article, log in using your NHS OpenAthens details.
Meniscal tears often accompany knee osteoarthritis, a disabling condition affecting 14 million individuals in the United States. While several randomized controlled trials have compared physical therapy to surgery for individuals with knee pain, meniscal tear, and osteoarthritic changes (determined via radiographs or magnetic resonance imaging), no trial has evaluated the efficacy of physical therapy alone in these subjects. Open Access.
To assess structural progression in knees with no/mild radiographic osteoarthritis (OA) (i.e., Kellgren/Lawrence [K/L] grades 0–2) that will undergo knee replacement during a 5‐year period; to assess differences in structural damage on magnetic resonance imaging (MRI) in knees with no/mild radiographic OA versus those with severe radiographic OA (i.e., K/L grades 3 and 4) at baseline; and to assess differences in pain levels between those groups. To read the full article, log in using your NHS OpenAthens details.