This study indicates that there is no significant association between the use of hydroxychloroquine and the risk of osteoporosis in patients with rheumatoid arthritis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
To assess the global and regional burden, long-term trends, and potential risk factors of vaccines-associated six types of rheumatic diseases (ankylosing spondylitis, polymyalgia rheumatica, rheumatoid arthritis, Sjögren's syndrome, Systemic lupus erythematosus, Systemic scleroderma), this study conducted disproportionality analysis based on the reports from the World Health Organization International Pharmacovigilance Database documented between 1967 and 2023 across 156 countries and territories. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study compares the effectiveness of Janus kinase inhibitors and biologic disease-modifying anti-rheumatic drugs on pain in patients with rheumatoid arthritis. Open access article - no login required.
This study investigates the relationship between weight loss rate following the initiation of anti-obesity medications and the risk of incident gout and recurrent gout flares among overweight/obese individuals. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study assessed the efficacy and safety of intravenous secukinumab for the treatment of adults with active axial spondyloarthritis in INVIGORATE-1. It found IV secukinumab was effective for the treatment of adults with active axSpA over 52 weeks. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This UK study investigated the temporal association between first diagnosis of gout and cardiovascular events in the short-term. It found a short-term increased risk of cardiovascular events in the 30 days following the first consultation at which gout was diagnosed. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The aim of this commentary is to discuss the Cochrane Review “Exercise therapy for treatment of acute non-specific low back pain” by IJzelenberg et al. Open access article - no login required.
This review explores the various pathophysiological mechanisms involved in statin-associated muscle symptoms and understand the difference between self-limited toxic myopathy and immune-mediated myopathy requiring immunomodulatory therapy. Open access article - no login required.
This study evaluates current practice relating to bone health in adult patients with inflammatory idiopathic myopathies in the United Kingdom and Hong Kong. Open access article - no login required.
This study aims to assess the correlation between the second metacarpal cortical index (2MCI) and bone mineral density (BMD) in rheumatoid arthritis patients, and to evaluate machine learning models utilizing 2MCI and clinical parameters for predicting osteoporosis/osteopenia presence and BMD. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study aimed to establish a population pharmacokinetic model for long-term HCQ treatment in patients with rheumatic diseases and to identify the factors influencing HCQ metabolism. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
In this emulated clinical trial, SGLT2i vs. DPP4i use was associated with significantly reduced risks of several cardiorenal complications among patients with both SLE and T2D. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study determines if metabolic syndrome, its components, and adipokines (adiponectin, leptin, Fibroblast Growth Factor-21) were associated with response to advanced therapies among patients with rheumatoid arthritis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study concludes olokizumab is effective in reducing rheumatoid arthritis activity and controlling chronic pain related to dysfunction of the nociceptive system. Open access article - no login required.
This study evaluates the risk of liver fibrosis and associated factors with the non-invasive fibrosis score-4 index in patients with inflammatory arthritis using methotrexate. Open access article - no login required.
This study aims to characterize non-articular pain at early rheumatoid arthritis diagnosis, the evolution over the first year of treatment, associations with active rheumatoid arthritis inflammation and impact on remission. Open access article - no login required.
This article reviews current knowledge on the effects of exercise on bone health in patients with autoimmune inflammatory rheumatic diseases, particularly in those experiencing a high corticosteroid burden. It also discusses potential mechanisms underlying the benefits of physical activity/exercise on bone tissue. Open access article - no login required.
Adult-onset Still's disease (AOSD) is systemic autoinflammatory disorder of unknown aetiology. Genetic studies have been limited. Here, we conducted detailed genetic and inflammatory biomarker analysis of a large AOSD cohort to investigate the underlying pathology and identify novel targets for potential treatment. Open access article - no login required.
This study aimed to characterize the incidence, risk factors and outcomes of late-onset systemic sclerosis-interstitial lung disease. Open access article - no login required.
Previous research has revealed connections between ankylosing spondylitis (AS) and comorbid conditions. However, observational studies frequently encounter difficulties in establishing definitive causal links between potential risk factors and AS. In contrast, Mendelian randomization (MR) offers a more robust approach to exploring causality by leveraging the random allocation of alleles at birth, thereby minimizing confounding factors. Open access article - no login required.