This study aimed to utilize Mendelian randomization (MR) methods to investigate the potential causal relationship between autoimmune liver disease and Sjogren's syndrome. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study investigates the clinical features of patients with rheumatic and musculoskeletal diseases (RMDs) infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the relationship between RMDs relapse and SARS-CoV-2 infection. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study uses UK Biobank data to reveal a positive correlation between accelerated biological aging, as measured by biological age accelerations, and the susceptibility to rheumatoid arthritis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study aimed to explore the hotspots of miRNA research related to RA published from different countries, organizations, and authors. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The study demonstrates the potential of integrating traditional biomarkers with unsupervised clustering algorithms in understanding the heterogeneity of AoSD. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study investigates the linkage of matrix metalloproteinase (MMP) gene polymorphisms with the pathogenesis of knee osteoarthritis (OA). Open access article - no login required.
This study aims to evaluate the long-term efficacy, safety, and cumulative retention rate of antitumor necrosis factor-alpha (anti-TNF-α) therapy for patients with Behcet's uveitis (BU) using meta-analysis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This article discusses the current understanding of genetic heritability and challenges in the diagnosis of rheumatic diseases and how this field may develop in the future. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Osteoarthritis (OA), rheumatoid arthritis (RA), and psoriatic arthritis (PsA) can all lead to the formation of bony proliferations (BP). This systematic review aimed to examine the characteristics of BPs in patients with RA, PsA, OA, and healthy controls (HC), and examined any treatment-related effect on BP number and size. Open access article - no login required.
This systematic review aimed to evaluate the extent of measurable and nonmeasurable factors in patients with rheumatoid arthritis and their satisfaction with this method of care. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This meta-analysis was performed to evaluate the clinical outcomes in rheumatoid arthritis patients with COVID-19. Our data suggests that RA patients had an increased risk of adverse clinical outcomes with COVID-19 infection. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Two years after trial termination, vitamin D 2000 IU/day's protective effects dissipated, but 1000 mg/day n-3 fatty acids had a sustained effect in reducing AD incidence. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
While there are still many unknowns that necessitate additional investigation, this article offers updated guidance to clinicians for enhancing clinical outcomes in immunocompromised populations with COVID-19. Open access article - no login required.
This systematic review investigates what is known about the positive and negative predictors of outcomes in patients with osteoarthritis who undergo intra‐articular corticosteroid injections. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This editorial looks at therapeutic drugs for gout. Although various therapies are available for gout treatment, the target of healing gout is often not achieved. Gout treatment often requires long-term medication, drug safety requires special attention. Open access article - no login required.
This study investigates the effect of an intensive dietary intervention on body weight and clinical measures of gout severity in individuals with obesity and gout. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This article incorporates and evaluates public and health professional involvement in a mixed methods review of occupational therapy for self-management of rheumatoid arthritis (RA). Open access article - no login required.
Uveitis is a common extra-articular manifestation of axial spondylarthritis (AxSpA). We set to evaluate risk of anterior uveitis (AU) with biologics and synthetic disease-modifying drugs in AxSpA. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study examines whether a mobile health patient reported outcome app integrated in the electronic health record (EHR) can reduce visit volume for rheumatoid arthritis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This population-based study investigated the incidence and factors associated with mental illness among patients with rheumatoid arthritis receiving b/tsDMARDs. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The aim of this study was to assess the correlation between adherence assessed with a Medication Event Monitoring System (MEMS) versus pill count, MTX-polyglutamate (PG) concentration and Compliance-Questionnaire-Rheumatology (CQR) in patients with established rheumatoid arthritis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
We aimed to examine the relation of the rate of weight loss induced by antiobesity medications over one year to all-cause mortality among patients with overweight or obesity and knee or hip OA. Open access article - no login required.
This article aims to evaluate the risk of all-cause, specific mortality among patients with fibromyalgia, which is a controversial topic. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The current study aims to assess the efficacy of baricitinib in treating SLE patients. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study aims to assess the association of obesity and CRP concentrations in adult patients with rheumatoid arthritis (RA), and its influence on measures of disease activity. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This summary is based on a Cochrane review previously published in the Cochrane Database of Systematic Reviews. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This guideline updates recommendations for prevention and treatment of glucocorticoid-induced osteoporosis (GIOP) for patients with rheumatic or nonrheumatic conditions receiving >3 months treatment with glucocorticoids (GCs) ≥2.5 mg daily. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study attempts to address an unmet area in myositis and pain research, and highlights the multidimensional and often overlooked area of pain perception in research. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The objective of this study is to summarize the available evidence, through meta-analysis, on the pain relief, quality of life, sleep improvement, and emotion regulation of fibromyalgia syndrome in traditional Chinese exercise, including Taichi. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study aimed to explore the applicability of SCT in and possible approaches to improving symptom appraisal and help-seeking of patients with ARDs, one of the key barriers to earlier diagnosis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The present study aims to measure the effect of the Mediterranean diet (MedDiet) on the disease activity scores (DAS28) among patients with rheumatoid arthritis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This guideline provides evidence-based recommendations regarding the optimal timing of TJA in patients who have symptomatic and radiographic moderate-to-severe osteoarthritis or advanced symptomatic osteonecrosis with secondary arthritis for whom nonoperative therapy was ineffective. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This randomized, controlled, mechanistic trial was designed to assess CBT's effects on pain catastrophizing and its underlying brain circuitry. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
There have been major changes in the classification and treatment of patients with idiopathic inflammatory myositis (IIM) in the last 2 decades. Here, we have longitudinally followed a well-characterized cohort of IIM patients in a rheumatology center and reported the outcome using the validated tools. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This item assesses the efficacy and safety of arthroscopic surgery associated with platelet-rich plasma (PRP) infusion in treating knee osteoarthritis (KOA). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
To address sub-optimal cardiovascular risk prediction in patients with psoriatic disease (PsD), we developed and internally validated a 5-year disease-specific cardiovascular risk prediction model. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Research has shown that empathy for both somatic and psychological pain recruits affective components of the so-called pain matrix, a set of brain regions that is activated during the perception of somatic pain. In addition, the subjective evaluation of experimentally induced somatic pain is related to empathy for somatic pain. In contrast, it is unclear whether or not the subjective sensitivity to somatic pain impacts on empathy for psychological pain.
In this article we review the pathogenesis and clinical features of the different TMA-causing conditions. We outline a practical approach to diagnosis and management and discuss empiric and disease-specific treatment strategies. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
We aimed to develop a risk prediction model for the development of PsA and to assess its performance among patients with psoriasis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study investigates the impact of high-dose glucocorticoid therapy on sarcopenia in hospitalized patients with rheumatic musculoskeletal diseases (RMDs). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The item concludes that, in children and adolescents with ERA and JPsA, secukinumab demonstrated significantly longer time to flare and number of flares versus placebo. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Old age and glucocorticoid (GC) use increase the susceptibility to infection in patients with rheumatoid arthritis (RA). Accordingly, we investigated whether GC discontinuation reduces the incidence of infection in older adults with RA and analyzed factors associated with GC discontinuation. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This effort aimed to develop evidence-based and consensus-based points to consider to assist clinicians in optimising decision-making in the early stages of diagnosis, treatment and monitoring of HLH/MAS. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This editorial discusses new clinical practice guidelines by the American College of Rheumatology and American Academy of Hip and Knee Surgeons. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This editorial looks at negative results of a clinical trial featured in this issue, alongside previous, more positive studies of VNS. They discussed questions raised by the topic. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study evaluated the influence of sarcopenia, especially muscle quality, on outcomes of antineutrophil cytoplasmic antibody-associated vasculitis (AAV). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study investigates whether baseline joint space narrowing (JSN) predicted disease remission, knee pain, and physical function changes in persons with knee osteoarthritis (OA). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The objective of this study is to explore the performance and effect of dual-energy computed tomography (CT) and ultrasound in the diagnosis of gouty arthritis and to provide a reference for the clinical diagnosis of gouty arthritis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Interstitial lung disease (ILD) is a frequent complication of rheumatoid arthritis (RA) that is associated with a significant increase in mortality. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study of 46 patients concludes that pelvic floor training should be included in rehabilitation programs to improve sexual function and pelvic floor dysfunctions for patients with pSS. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This systematic review and meta-analysis aims to comprehensively investigate the immunogenicity of these vaccines in patients with autoimmune inflammatory rheumatoid diseases (AIRDs). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This review aimed to collate and synthesize the current evidence of environmental factors associated with juvenile idiopathic arthritis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This commentary discusses the Cochrane Review 'Adjunctive therapies in addition to land-based exercise therapy for osteoarthritis of the hip or knee', published by the Cochrane Musculoskeletal Group. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study evaluates predictors for successful biologic tapering among patients with inflammatory arthritis (IA) using baseline characteristics from the BIODOPT trial. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Although ChatGPT is reliable and useful for patients to obtain information about rheumatic diseases, it should be kept in mind that it may give false and misleading answers. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Our study indicates that gastrointestinal surgeries have limited age- and sex-related effects on psoriasis. These findings provide new insights into the risk of developing psoriasis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
We estimate the causal effect of body mass index (BMI) on the risk of developing five different rheumatic diseases. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Our results suggest there is an advantage in using ePROM monitoring in patients with IA, with potential for reduction in healthcare resource use without detrimental impact in disease outcomes. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This guideline provides initial ACR recommendations on integrative interventions for the management of rheumatoid arthritis to accompany disease-modifying antirheumatic drug treatments. The broad range of interventions included in these recommendations illustrates the importance of an interprofessional, team-based approach to RA management. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Conclusions
Although ChatGPT is reliable and useful for patients to obtain information about rheumatic diseases, it should be kept in mind that it may give false and misleading answers.
To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
We assessed the efficacy of CZP in patients with early and established RA across baseline RF levels. CZP treatment may be considered in patients with RA irrespective of baseline RF levels and time from diagnosis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Brepocitinib 30 and 60 mg QD were superior to placebo at reducing signs and symptoms of PsA. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This ancillary study of the MAINRITSAN 2 trial aimed to explore the relationship between rituximab plasma concentration, genetic polymorphisms in PK/PD candidate genes, and clinical outcomes. These results suggest that drug monitoring could be useful to individualize the schedule of rituximab administration within the maintenance phase. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Our study indicates a high prevalence of RLS in patients with rheumatic diseases. Early detection and treatment of RLS in patients with rheumatic conditions could be beneficial in improving their overall health and quality of life. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study aims to explore the association between physical capacity tests explored in the consultation and the level of disability in women with fibromyalgia. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Exercise training is crucial for managing ankylosing spondylitis. We evaluated the effects of exercise with different levels of supervision on clinical outcomes in patients with ankylosing spondylitis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This systematic review aimed to investigate the correlates of sedentary behaviour in people with fibromyalgia using the socio-ecological model. This systematic review aimed to investigate the correlates of SB in PwF using the socio-ecological model.
In this review, we discuss autophagic imbalance in RA and the regulatory mechanisms of circRNAs. We also explore possible targets for circRNA regulation of autophagy in RA. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
We reviewed the impact of key SDH on SLE presentation, management and outcomes, including income, education, neighbourhood factors, healthcare access, discrimination and social support. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
We aimed to assess attitudes and factors affecting the decision-making vis-à-vis COVID-19 vaccination among patients with autoimmune rheumatic diseases (ARDs). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
To compare pain intensity among individuals with idiopathic inflammatory myopathies (IIMs), other systemic autoimmune rheumatic diseases (AIRDs), and without rheumatic disease (wAIDs). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
For patients with connective tissue disease-associated interstitial lung disease (CTD-ILD), early medical intervention would be desirable. This study analyzed the real-world, single-center use of nintedanib for CTD-ILD patients. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
We aimed to investigate the effect of targeted therapies on cardiovascular risk in psoriasis (PsO) and psoriatic arthritis (PsA) via a meta-analysis of randomized controlled trials (RCTs). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Frailty and pre-frailty are commonly detected in middle-aged individuals with axSpA. Our findings highlight a possible need for frailty screening and preventive programs targeting middle-aged axSpA patients. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The aim of this commentary is to discuss from a rehabilitation perspective the Cochrane Review “Non-steroidal anti-inflammatory drugs for acute gout” by van Durme et al,
published by Cochrane Musculoskeletal Group. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This retrospective cohort study aimed to evaluate the effect of the interaction between methotrexate and glucocorticoids on the risk of developing bacterial infections in patients with rheumatoid arthritis (RA) using biological disease-modifying antirheumatic drugs (bDMARDs). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
There is a growing interest in studying the effects of arthritis on a person's work productivity using a growing variety of outcome indicators. This study looks at the development of a valid and reliable shortened version of the Workplace Activity Limitation Scale 12 (WALS-12) for assessing work productivity limitations in rheumatoid arthritis (RA) patients. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This systematic review looks at the available evidence on APO in patients who subsequently were diagnosed with a rheumatic disease to identify whether there is an increased risk in pre-ARD. Findings of an increased risk of APO in certain pre-ARDs highlight the relevance of taking an obstetric history during the first rheumatology appointment and the need for novel screening strategies for the prediction of APOs. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This survey aims to quantify preferences for preventive therapies for rheumatoid arthritis (RA) across three countries: UK, Germany and Romania. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Knee pain is the most frequently reported type of lower extremity pain among children and adolescents. The objective of this study was to establish the features distinguishing inflammatory knee pain from non-inflammatory knee pain and to determine the specific variables to consider in suspected juvenile idiopathic arthritis (JIA). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Poor adherence to allopurinol among people with gout contributes to suboptimal gout management. This study sought to understand the facilitators and barriers to allopurinol adherence across the three stages of medication adherence, and patient perspectives on strategies to improve adherence. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The aim of this study was to explore the factors associated with subjective knee stiffness in patients with knee osteoarthritis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
A systematic review and meta-analysis of cohort studies were conducted to comprehensively assess the associations between gout and venous thromboembolism and its subtypes, deep venous thrombosis and pulmonary embolism. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
By performing a meta-analysis of published cohort studies, this review aims to evaluate the association between gouty arthritis (GA) and the risk of myocardial infarction (MI) and heart failure (HF), hence providing evidence for clinical management. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Aim: To compare (a) the change in radiological bony morphology between participants with femoroacetabular impingement (FAI) syndrome who underwent arthroscopic hip surgery compared to physiotherapist-led non-surgical care and (b) the change in radiological bony morphology between participants with FAI syndrome who underwent arthroscopic hip surgery involving cam resection or acetabular rim trimming or combined cam resection and acetabular rim trimming. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Walking in the community allows participation in meaningful activities which positively influences self-rated health and quality of life. Our objective was to identify factors associated with social participation and community ambulation in a representative sample of Canadian adults with osteoarthritis (OA). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Aim: To summarise the effectiveness of organisational interventions on appropriate opioid prescribing for non-cancer pain upon hospital discharge. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The aims of this study were to explore the immediate effect of two types of braces, a pneumatic knee brace with air pressure embedded in a sandal cuff (sandal cuff pressure) and a conventional knee brace on gait, pain and satisfaction during walking in patients with knee medial osteoarthritis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
To assess the efficacy of rituximab (RTX) on lung function and the prevalence of adverse events (AEs) in connective tissue disease-associated interstitial lung disease (CTD-ILD) by meta-analysis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
To analyze the clinical patterns of new-onset inflammatory arthritis after COVID-19 vaccination among patients without pre-existing rheumatic or autoimmune diseases. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
To describe the clinical and laboratory features of Sjögren's syndrome (SS) with renal tubular acidosis (RTA) from published literature. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Many patients with polyarteritis nodosa (PAN) complicated by digital gangrene have poor outcomes and related research information is limited. Our aim is to identify the associated risk and prognostic factors in PAN patients with digital gangrene. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
YLB113 biosimilar was evaluated in an open-label extension single-arm study to assess long-term safety, efficacy, and immunogenicity in patients with rheumatoid arthritis (RA). We also report post-hoc results on the incidence of injection-site reactions (ISRs) and injection-site erythema (ISE) from a phase III study. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Knowledge gaps exist around diagnostic and treatment approaches for patients admitted to hospital with low back pain. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The aim of this study was to assess the safety and efficacy of Janus kinase inhibitors (JAKi), in the management of key clinical domains of PsA including peripheral arthritis, psoriasis, enthesitis and dactylitis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This issue of the Journal is primarily focused on new advances in the diagnosis and treatment of opioid use disorder. The issue begins with an overview by Drs. Cecilia Bergeria and Eric Strain from Johns Hopkins University (1) that discusses the prevalence of opiate use disorder and associated lethal overdoses as well as current pharmacologic and nonpharmacologic treatment approaches. Elsewhere in the issue, making the diagnosis of prescription-related opiate use disorder (POUD) can be challenging and in this regard a paper explores the impacts of modifying current criteria for POUD on prevalence rates. Another paper assesses the efficacy of buprenorphine/naloxone, primarily taken at home, for treating POUD. Also related to treatment, another paper characterizes the effects of COVID-19 telehealth policy changes related to buprenorphine treatment on VA patients with opiate use disorder. We also present papers in this issue that address the prevalence of cannabis use disorder in the VA population and the possibility of using a mindfulness-based intervention as a nonpharmacologic treatment for pain. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV) are vulnerable to opportunistic infections, including cytomegalovirus (CMV) infection. This narrative review aims to identify factors associated with CMV infection in patients with AAV. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The objectives of this study are to ascertain the determinants of quality of life (QoL) and hand function among persons with hand osteoarthritis (OA) and to assess the influence of hand function on QoL among persons with OA. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Secukinumab, the first IL-17A inhibitor, is widely used to treat immune diseases, including plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. Here, we aimed to explore the clinical characteristics, outcomes, and time to onset of the four main toxicities of secukinumab, using post-marketing data. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.