This study evaluates current practice relating to bone health in adult patients with inflammatory idiopathic myopathies in the United Kingdom and Hong Kong. Open access article - no login required.
This review explores the various pathophysiological mechanisms involved in statin-associated muscle symptoms and understand the difference between self-limited toxic myopathy and immune-mediated myopathy requiring immunomodulatory therapy. Open access article - no login required.
The aim of this commentary is to discuss the Cochrane Review “Exercise therapy for treatment of acute non-specific low back pain” by IJzelenberg et al. Open access article - no login required.
The aim of this scoping review was to identify factors influencing nurses’ acceptance of welfare technologies in institutional, home, or community settings. Open access article - no login required.
This realist evaluation explored how and in which circumstances supported self-management is enacted and delivered within community stroke rehabilitation. Open access article - no login required.
This study explored older adults’ experiences with the “My Health Plan” mHealth intervention and examined which person-level factors were associated with adherence. Open access article - no login required.
This study aimed to identify personal and contextual predictive factors for (1) discharge from hospital to different levels of supported accommodation and (2) self-directed support needs of individuals with serious mental illness once they are in supported accommodation in Scotland. Open access article - no login required.
This UK study investigated the temporal association between first diagnosis of gout and cardiovascular events in the short-term. It found a short-term increased risk of cardiovascular events in the 30 days following the first consultation at which gout was diagnosed. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study assessed the efficacy and safety of intravenous secukinumab for the treatment of adults with active axial spondyloarthritis in INVIGORATE-1. It found IV secukinumab was effective for the treatment of adults with active axSpA over 52 weeks. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study investigates the relationship between weight loss rate following the initiation of anti-obesity medications and the risk of incident gout and recurrent gout flares among overweight/obese individuals. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study compares the effectiveness of Janus kinase inhibitors and biologic disease-modifying anti-rheumatic drugs on pain in patients with rheumatoid arthritis. Open access article - no login required.
This study examines the accuracy and precision of the Montreal Cognitive Assessment in detecting cognitive impairment in a sample of patients with alcohol use disorder, and investigated whether the MoCA predicts premature discontinuation from treatment. Open access article - no login required.
This study aimed to explore GP experiences of safeguarding within care homes for older adults. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study used qualitative descriptive methodology to explore the experience of adults with aphasia with collaborative goal setting. The authors conclude that occupational therapy practitioners should support collaborative goal setting for people with aphasia through use of aphasia-friendly goal-setting processes, including adaptations to existing goal-setting measures as appropriate. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This article provides an overview of a service development project to develop a web-based application (app) to support non-mental health nurses when assessing the mental health needs and risks of children and young people. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This case series examines the use of a multimodal wound matrix (MWM) trialled in a selection of clinical practice settings and on a variety of hard-to-heal wounds. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Various technological advancements, including artificial intelligence, subepidermal moisture measurement, cytokine measurement, thermography and ultrasound are emerging as promising tools for pressure ulcer (PU) detection, and subsequent prevention of more serious PU damage. This article delves into these technologies, suggesting that they could lead healthcare in the right direction, toward optimal assessment and adoption of focused prevention strategies. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Broadening prediction efforts from imminent psychotic symptoms to neurodevelopmental vulnerabilities can enhance the accuracy of diagnosing severe mental disorders. Child and adolescent mental health services should lead a developmentally-sensitive model for timely, effective detection and intervention. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The study explores psychotherapists' attitudes towards new technologies and digital solutions. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This Cochrane review, first published in 2023, evaluates the benefits and harms of psychosocial interventions to reduce antipsychotic medication use in care home residents compared to regular care, optimised regular care, or a different psychosocial intervention. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Service users who have spent time in seclusion describe it as a negative experience, viewing it as punishment. A service evaluation was conducted at a medium secure adult mental health unit to better understand the current practices of occupational therapists working in seclusion. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study tested two hypotheses: (a) that there were significant group-level associations between post-ECT clinical outcomes and pre-ECT clinical variables and (b) that it was possible to develop a method for predicting illness remission for individual patients using machine learning. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study examines the relative re-hospitalisation rates for mental health relapse and adverse events associated with clozapine and other antipsychotics in adult and child/youth cohorts. Open access article - no login required.
The aim of this systematic review and meta-analysis is to examine the association between intolerance of uncertainty and specific psychological responses to the COVID-19 pandemic. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
How early in life stress-immune related environmental factors increase risk predisposition to schizophrenia remains unknown. We examined if pro-inflammatory changes perturb the brain epidermal growth factor (EGF) system, a system critical for neurodevelopment and mature CNS functions including synaptic plasticity. Open access article - no login required
Based on up-to-date evidence (as of January 2024), we present a rationale for the selection of “first-line treatments” for patients with early-stage schizophrenia and challenges surrounding the selection of these agents. We present a general rationale, such that when idiographic factors of individuals dictate a different approach, the considerations discussed here should defer to individualized plans, and patients and practitioners should engage in shared decision-making at every step... Open access article - no login required
Both the brain-derived neurotrophic factor (BDNF) valine (Val)/methionine (Met) polymorphism and mismatch negativity (MMN) amplitude are reportedly linked to working memory impairments in schizophrenia. However, there is evident scarcity of research aimed at exploring the relationships among the three factors. In this secondary analysis of a randomized, controlled, double-blind trial, we investigated these relationships. Open access article - no login required
We conducted a 10-year follow-up study of a comprehensive first-episode psychosis (FEP) cohort investigating the prevalence of clinical recovery (CR) and treatment resistance (TR) after ten years, as well as clinical, demographic, and pre-illness predictors of long-term outcomes. Open access article - no login required
Psychosis can be thought of as a threat-based experience. Compassion has been shown to be effective in reducing threat, although highly distressed individuals may struggle to be self-compassionate. This study explored the effects of compassionate interactions with staff on inpatients with psychosis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Although collective violence represents a significant public health concern, a limited number of longitudinal studies have addressed this topic, with no systematic reviews focusing on posttraumatic stress symptom (PTSS) trajectories. The present systematic review and meta-analyses examined PTSS prevalence and trajectories after exposure to collective violence. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) is a widely used, well-validated structured interview for posttraumatic stress disorder (PTSD). It was recently revised to improve various aspects of administration and scoring. We conducted a psychometric evaluation of the revised version, known as the CAPS-5-R. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Here, we introduce the use of “clinical checks” within an existing self-report measure. These are brief supplementary questions intended to clarify and confirm initial responses, similar to what occurs in a clinical interview. Open access article - no login required
We report the effect of quality of therapy delivery on outcomes in a randomized, controlled trial of behavioural activation (BA) and guided self-help (GSH) for depression in adults with intellectual disabilities. Open access article - no login required
The accommodation of symptoms of obsessive-compulsive disorder (OCD) by loved ones is highly prevalent and impactful on treatment outcomes; however, little is known about factors that influence accommodation by romantic partners of OCD sufferers. The aim of this preliminary investigation was to explore such correlates. Open access article - no login required
This study aims to examine and synthesise the evidence for non-clinical services on improving functional outcomes for young adults with mental disorders. Open access article - no login required
This study aims to determine the effect of physical activity on cognitive restraint, uncontrolled eating and emotional eating in individuals with a psychotic disorder. Open access article - no login required
Researchers report varying levels of cognitive flexibility and theory of mind (ToM) deficiencies in adolescents with obsessive-compulsive disorder (OCD). This research set out to investigate the impact of these variables on the disorder's outcomes. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This paper aims to explore how the term “mental health literacy” (MHL) is defined and understand the implications for public mental health and educational interventions. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
In this study, we interviewed autistic mothers and professional midwives, living and working across the United Kingdom and Ireland. Open access article - no login required
This study adopted a qualitative method to develop themes arising from online forum discussions, using the words of autistic adults talking about how they experience and understand their self-harming behaviours. Open access article - no login required
Tabletop role-playing games (TTRPGs) are popular hobbies that may offer specific social benefits for autistic people. This study investigated the ability of TTRPGs to provide a safe space where autistic adults could develop relationships with other autistic adults while engaging in character and world-building. Open access article - no login required
In this study, we asked 60 autistic adults with varying degrees of face recognition ability to complete two tests of face recognition, a questionnaire about social anxiety and a bespoke survey which asked participants about their experiences of face recognition and social interaction. Open access article - no login required
The Autism Stigma and Knowledge Questionnaire (ASK-Q) was developed to assess autism knowledge across cultural contexts. The current study aimed to examine cultural equivalence of the measure using a large, international database. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
...the aims of this study were to investigate the feasibility of resting ECG recording, to study the prevalence of ECG abnormalities, and to compare the frequency of ECG abnormalities with medical records in older adults with ID. Open access article - no login required
Correlates of inactivity among the general and ID populations were identified through a literature scoping review. Open access article - no login required
We assessed drug burden in a cohort of sequential referrals to a national memory service for people with ID. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The current study aimed to compare the effectiveness of training in IVR and a non-immersive virtual environment for improving real-world skills in people with ID. Open access article - no login required
Current scales are often lengthy and redundant, leading to exhaustion and response burden. The goal is to use machine learning techniques, specifically item-reduction methods and selection algorithms, to develop shorter and more efficient scales. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Standardization of medication discharge plan (MDP) is lacking. This study aimed to (1) create a standardized MDP for older adults using consensus-based principles, (2) create a short-version MDP and (3) generate a practical guide. Open access article - no login required
This study describes the pharmacokinetic (PK)/target engagement (TE) relationship of tozorakimab, an anti-interleukin (IL)-33 antibody, by building a mechanistic population PK/TE model using phase 1 biomarker data. Open access article - no login required
Previous systematic reviews suggest that deprescribing may improve survival, particularly in frail older people. Evidence is rapidly accumulating, suggesting a need for an updated review of the literature. Open access article - no login required
We aimed to clarify the effectiveness and safety of the biosimilar teriparatide compared with those of the reference product using the incidence of new fractures and osteosarcoma as outcomes in osteoporosis patients. Open access article - no login required
The alcohols methanol, ethylene glycol and diethylene glycol share many characteristics... To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The aim of this study was to assess the ChatGPT-4 (ChatGPT) large language model (LLM) on tasks relevant to community pharmacy. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The purpose of this scoping review is to summarize literature which has addressed sex/gender differences in relation to the confluence of OUD and chronic pain. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
To assess the global and regional burden, long-term trends, and potential risk factors of vaccines-associated six types of rheumatic diseases (ankylosing spondylitis, polymyalgia rheumatica, rheumatoid arthritis, Sjögren's syndrome, Systemic lupus erythematosus, Systemic scleroderma), this study conducted disproportionality analysis based on the reports from the World Health Organization International Pharmacovigilance Database documented between 1967 and 2023 across 156 countries and territories. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study explores the role of champions in implementing community-based interventions for older adults with chronic conditions. Open access article - no login required.
Research designed to establish alcohol and other drug (AOD) mechanisms of behavioral change (MOBC) has centered on what variables mediate the relation between AOD treatment and outcomes. The purpose of this paper was to review this research evidence to identify empirically supported mediators of alcohol and other drug use and related outcomes and then to evaluate their potential as being AOD treatment MOBC. Open access article - no login required.
Patients with alcohol use disorder (AUD) tend to selectively approach alcohol cues in the environment, demonstrating an alcohol-approach bias. Alcohol-approach-bias modification (Alcohol-ApBM) effectively increases abstinence rates in patients with AUD when added to abstinence-focused treatment, but the evidence for its proposed working mechanism is limited. This study examined whether changes in approach-avoidance tendencies over the course of Alcohol-ApBM would predict abstinence after inpatient treatment. Open access article - no login required.
This study reviews evidence from a broad range of fields to unravel to what extent, and how, socioeconomic health inequalities are intergenerationally transmitted. Open access article - no login required.
This study investigates the potential impacts of child poverty reduction scenarios on population health and health inequalities in England between 2024 and 2033. Open access article - no login required.
Frailty, a state of increased vulnerability to adverse health outcomes, has garnered significant attention in research and clinical practice. Existing constructs aggregate clinical features or health deficits into a single score. While simple and interpretable, this approach may overlook the complexity of frailty and not capture the full range of variation between individuals. Open access article - no login required.
This review examines the effect of therapists' internalized relational models on the treatment process (e.g., therapeutic alliance and countertransference) and treatment outcomes (e.g., symptoms and functioning). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study investigates the effects of mentalization-based therapy and the unified protocol on individuals with cooccurring antisocial personality disorder and borderline personality disorder. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study indicates that there is no significant association between the use of hydroxychloroquine and the risk of osteoporosis in patients with rheumatoid arthritis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study provides a real-world example of intervention-mapping, systematically developing an occupational therapy intervention to empower adolescents to adopt healthier time-use behaviours to improve their mental health. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Sensors commonly used to record sub-bandage pressures may be less reliable than is commonly believed. In this review, the various calibration methods referenced in the literature are briefly described and the limitations of each discussed. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study evaluates the effectiveness of topical application of basic fibroblast growth factor (bFGF) on pressure ulcers (PUs). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study evaluates the effectiveness of psychological interventions (CBT, EMDR, expressive/art, mindfulness, mixed elements, NET and psychoeducation) in reducing symptoms of PTSD, depression, and anxiety in forced migrants. Open access article - no login required.
Social science researchers continue to choose scoping reviews as a means of synthesizing the literature in their field, though search reporting is inconsistent. Many projects could benefit from the application of tools such as PRISMA-S, use of supplementary search strategies, and support of an LIS professional. Open Access
'Searchsmart.org is a free website that guides researchers to particularly suitable search options for their particular disciplines, offering a wide array of resources, including search engines, aggregators, journal platforms, repositories, clinical trials databases, bibliographic databases, and digital libraries. Search Smart currently evaluates the coverage and functionality of more than a hundred leading scholarly databases, including most major multidisciplinary databases and many that are discipline-specific'
...assessments required to diagnose constipation in a person with a learning disability accurately. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This article identifies some of the barriers to effective service provision for people with learning disabilities in primary care. It describes how learning disability nurses and learning disability support workers can assist staff in primary care to improve the experiences of people with learning disabilities when attending healthcare appointments such as annual health checks, blood tests, cancer screening and other routine investigations. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
People with learning disabilities are more likely than the general population to develop type 2 diabetes, but are less likely to receive appropriate care.... To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Nearly one in three NHS trusts in England (29%) does not have a specific acute learning disability liaison service with a learning disability registered nurse, according to our exclusive investigation. This means that for many of the estimated 1.5 million people with learning disabilities in England, when they attend an acute hospital for treatment there will not be a clinician with specialist skills on hand to help meet their healthcare and communication needs. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Of the 2,054 deaths in people with a learning disability, 853 (42%) were avoidable. The report... To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study aims to identify a consensus among experts regarding what conditions are conducive to successful sexual support and education for adults with mild IDs. Open access article - no login required
This article represents a quantitative synthesis of the current state of the literature on emotion dysregulation, with a specific focus on how the severity of emotion dysregulation differs across autistic and non-autistic people across the lifespan. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
In this study, we explored a model that included several individual psychological factors (such as fear of being negatively judged, self-esteem and autistic identity) and broader social and cultural factors (such as perceived stigma, negative life events, cultural emphasis on conformity and desire to fit in or stand out). Open access article - no login required
This codesigned review consolidated the evidence on the healthcare experiences of individuals and their carers from ethnic minority backgrounds with a learning disability. Open access article - no login required
Research has shown that not everyone can easily access digital content, particularly people with intellectual disabilities. Despite internet access being recognised as a human right in the United Nations' Conventions on the Rights of Persons with Disabilities, this group faces significant disadvantages... Open access article - no login required
This umbrella review aims to establish whether the passport is an effective reasonable adjustment, identify barriers to its use and make recommendations to alleviate these barriers. Open access article - no login required
The aim of this scoping review was to understand stressful life events and their relationship with PTSD symptoms, other mental health and/or behavioural problems in individuals with ID-BIF. Open access article - no login required
To investigate: (i) whether mood states associated with bipolar disorder are associated with poorer quality of life in older adults, and (ii) what are some of the predictors of quality of life in older adults with mood states associated with bipolar disorder. Open access article - no login required
...consistent evidence about patients' commitment is missing. The present meta-analysis addresses this gap by systematically comparing drop-out rates in animal-assisted psychotherapy and by relating the resulting across study drop-out rate to across study drop-out rates reported in meta-analyses on conventional psychotherapy. Open access article - no login required
We worked alongside services to understand barriers and facilitators of the implementation of cognitive therapy for PTSD (a type of tf-CBT) to CEYP. Open access article - no login required
We constructed a parameterized, rate-based neural model of on-center/off-surround neurons in the early visual system to investigate the impacts of changes to the excitatory and inhibitory receptive field subfields. Open access article - no login required
It remains unclear whether unmedicated and medicated individuals with schizophrenia would share common neuroanatomy-cognition associations. Therefore, we aimed to investigate multivariate neuroanatomy-cognition relationships in both groups. Open access article - no login required
A Finnish research study found that people with bipolar disorder have a higher risk of death from factors such as self harm and accidents, as well as from physical health issues.
...we tested whether hippocampal subfield volume deficits link with deviations in glucose metabolism commonly seen in early psychosis, and whether the glucose parameters or subfield volumes change during follow-up period using one-year longitudinal study design of 78 first-episode psychosis patients (FEP), 48 clinical high-risk patients (CHR) and 83 controls (CTR). Open access article - no login required
To compare psychotic-like experiences (PLEs) in adolescents and young adults referred to the Mental Health Services (MHSs). Open access article - no login required
Since there are few studies on this topic, the goals of this examination were: (1) to calculate service disengagement rates in a CHR-P sample along 2-years of follow-up; and (2) to examine the most relevant predictive factors of disengagement at baseline. Open access article - no login required
The current pilot study aimed to evaluate whether individuals at CHR showed changes in emotional and stigma-related experiences following a CHR psychoeducation intervention, BEGIN: Brief Educational Guide for Individuals in Need. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The study was designed to assess the role of coping style and self-esteem in the context of different phases of schizophrenia. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.