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Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

K. Ellrott, M. Bailey, G. Saksena, K. Covington, C. Kandoth, C. Stewart, J. Hess, S. Ma, K. Chiotti, M. McLellan, H. Sofia, C. Hutter, G. Getz, D. Wheeler, L. Ding, S. Caesar-Johnson, J. Demchok, I. Felau, M. Kasapi, M. Ferguson, C. Hutter, H. Sofia, R. Tarnuzzer, Z. Wang, L. Yang, J. Zenklusen, J. Zhang, S. Chudamani, J. Liu, L. Lolla, R. Naresh, T. Pihl, Q. Sun, Y. Wan, Y. Wu, J. Cho, T. DeFreitas, S. Frazer, N. Gehlenborg, G. Getz, D. Heiman, J. Kim, M. Lawrence, P. Lin, S. Meier, M. Noble, G. Saksena, D. Voet, H. Zhang, B. Bernard, N. Chambwe, V. Dhankani, T. Knijnenburg, R. Kramer, K. Leinonen, Y. Liu, M. Miller, S. Reynolds, I. Shmulevich, V. Thorsson, W. Zhang, R. Akbani, B. Broom, A. Hegde, Z. Ju, R. Kanchi, A. Korkut, J. Li, H. Liang, S. Ling, W. Liu, Y. Lu, G. Mills, K. Ng, A. Rao, M. Ryan, J. Wang, J. Weinstein, J. Zhang, A. Abeshouse, J. Armenia, D. Chakravarty, W. Chatila, I. de Bruijn, J. Gao, B. Gross, Z. Heins, R. Kundra, K. La, M. Ladanyi, A. Luna, M. Nissan, A. Ochoa, S. Phillips, E. Reznik, F. Sanchez-Vega, C. Sander, N. Schultz, R. Sheridan, S. Sumer, Y. Sun, B. Taylor, J. Wang, H. Zhang, P. Anur, M. Peto, P. Spellman, C. Benz, J. Stuart, C. Wong, C. Yau, D. Hayes, Parker, M. Wilkerson, A. Ally, M. Balasundaram, R. Bowlby, D. Brooks, R. Carlsen, E. Chuah, N. Dhalla, R. Holt, S. Jones, K. Kasaian, D. Lee, Y. Ma, M. Marra, M. Mayo, R. Moore, A. Mungall, K. Mungall, A. Robertson, S. Sadeghi, J. Schein, P. Sipahimalani, A. Tam, N. Thiessen, K. Tse, T. Wong, A. Berger, R. Beroukhim, A. Cherniack, C. Cibulskis, S. Gabriel, G. Gao, G. Ha, M. Meyerson, S. Schumacher, J. Shih, M. Kucherlapati, R. Kucherlapati, S. Baylin, L. Cope, L. Danilova, M. Bootwalla, P. Lai, D. Maglinte, D. Berg, D. Weisenberger, J. Auman, S. Balu, T. Bodenheimer, C. Fan, K. Hoadley, A. Hoyle, S. Jefferys, C. Jones, S. Meng, P. Mieczkowski, L. Mose, A. Perou, C. Perou, J. Roach, Y. Shi, J. Simons, T. Skelly, M. Soloway, D. Tan, U. Veluvolu, H. Fan, T. Hinoue, P. Laird, H. Shen, W. Zhou, M. Bellair, K. Chang, K. Covington, C. Creighton, H. Dinh, H. Doddapaneni, L. Donehower, J. Drummond, R. Gibbs, R. Glenn, W. Hale, Y. Han, J. Hu, V. Korchina, S. Lee, L. Lewis, W. Li, X. Liu, M. Morgan, D. Morton, D. Muzny, J. Santibanez, M. Sheth, E. Shinbrot, L. Wang, M. Wang, D. Wheeler, L. Xi, F. Zhao, J. Hess, E. Appelbaum, M. Bailey, M. Cordes, L. Ding, C. Fronick, L. Fulton, R. Fulton, C. Kandoth, E. Mardis, M. McLellan, C. Miller, H. Schmidt, R. Wilson, D. Crain, E. Curley, J. Gardner, K. Lau, D. Mallery, S. Morris, J. Paulauskis, R. Penny, C. Shelton, T. Shelton, M. Sherman, E. Thompson, P. Yena, J. Bowen, J. Gastier-Foster, M. Gerken, K. Leraas, T. Lichtenberg, N. Ramirez, L. Wise, E. Zmuda, N. Corcoran, T. Costello, C. Hovens, A. Carvalho, A. de Carvalho, J. Fregnani, A. Longatto-Filho, R. Reis, C. Scapulatempo-Neto, H. Silveira, D. Vidal, A. Burnette, J. Eschbacher, B. Hermes, A. Noss, R. Singh, M. Anderson, P. Castro, M. Ittmann, D. Huntsman, B. Kohl, X. Le, R. Thorp, C. Andry, E. Duffy, V. Lyadov, O. Paklina, G. Setdikova, A. Shabunin, M. Tavobilov, C. McPherson, R. Warnick, R. Berkowitz, D. Cramer, C. Feltmate, N. Horowitz, A. Kibel, M. Muto, C. Raut, A. Malykh, J. Barnholtz-Sloan, W. Barrett, K. Devine, J. Fulop, Q. Ostrom, K. Shimmel, Y. Wolinsky, A. Sloan, A. Rose, F. Giuliante, M. Goodman, B. Karlan, C. Hagedorn, J. Eckman, J. Harr, J. Myers, K. Tucker, L. Zach, B. Deyarmin, H. Hu, L. Kvecher, C. Larson, R. Mural, S. Somiari, A. Vicha, T. Zelinka, J. Bennett, M. Iacocca, B. Rabeno, P. Swanson, M. Latour, L. Lacombe, B. Têtu, A. Bergeron, M. McGraw, S. Staugaitis, J. Chabot, H. Hibshoosh, A. Sepulveda, T. Su, T. Wang, O. Potapova, O. Voronina, L. Desjardins, O. Mariani, S. Roman-Roman, X. Sastre, M. Stern, F. Cheng, S. Signoretti, A. Berchuck, D. Bigner, E. Lipp, J. Marks, S. McCall, R. McLendon, A. Secord, A. Sharp, M. Behera, D. Brat, A. Chen, K. Delman, S. Force, F. Khuri, K. Magliocca, S. Maithel, J. Olson, T. Owonikoko, A. Pickens, S. Ramalingam, D. Shin, G. Sica, E. Meir, H. Zhang, W. Eijckenboom, A. Gillis, E. Korpershoek, L. Looijenga, W. Oosterhuis, H. Stoop, K. van Kessel, E. Zwarthoff, C. Calatozzolo, L. Cuppini, S. Cuzzubbo, F. DiMeco, G. Finocchiaro, L. Mattei, A. Perin, B. Pollo, C. Chen, J. Houck, P. Lohavanichbutr, A. Hartmann, C. Stoehr, R. Stoehr, H. Taubert, S. Wach, B. Wullich, W. Kycler, D. Murawa, M. Wiznerowicz, K. Chung, W. Edenfield, J. Martin, E. Baudin, G. Bubley, R. Bueno, A. Rienzo, W. Richards, S. Kalkanis, T. Mikkelsen, H. Noushmehr, L. Scarpace, N. Girard, M. Aymerich, E. Campo, E. Giné, A. Guillermo, N. Bang, P. Hanh, B. Phu, Y. Tang, H. Colman, K. Evason, P. Dottino, J. Martignetti, H. Gabra, H. Juhl, T. Akeredolu, S. Stepa, D. Hoon, K. Ahn, K. Kang, F. Beuschlein, A. Breggia, M. Birrer, D. Bell, M. Borad, A. Bryce, E. Castle, V. Chandan, J. Cheville, J. Copland, M. Farnell, T. Flotte, N. Giama, T. Ho, M. Kendrick, J. Kocher, K. Kopp, C. Moser, D. Nagorney, D. O'Brien, B. O'Neill, T. Patel, G. Petersen, F. Que, M. Rivera, L. Roberts, R. Smallridge, T. Smyrk, M. Stanton, R. Thompson, M. Torbenson, J. Yang, L. Zhang, F. Brimo, J. Ajani, A. Gonzalez, C. Behrens, J. Bondaruk, R. Broaddus, B. Czerniak, B. Esmaeli, J. Fujimoto, J. Gershenwald, C. Guo, A. Lazar, C. Logothetis, F. Meric-Bernstam, C. Moran, L. Ramondetta, D. Rice, A. Sood, P. Tamboli, T. Thompson, P. Troncoso, A. Tsao, I. Wistuba, C. Carter, L. Haydu, P. Hersey, V. Jakrot, H. Kakavand, R. Kefford, K. Lee, G. Long, G. Mann, M. Quinn, R. Saw, R. Scolyer, K. Shannon, A. Spillane, J. Stretch, M. Synott, J. Thompson, J. Wilmott, H. Al-Ahmadie, T. Chan, R. Ghossein, A. Gopalan, D. Levine, V. Reuter, S. Singer, B. Singh, N. Tien, T. Broudy, C. Mirsaidi, P. Nair, P. Drwiega, J. Miller, J. Smith, H. Zaren, J. Park, N. Hung, E. Kebebew, W. Linehan, A. Metwalli, K. Pacak, P. Pinto, M. Schiffman, L. Schmidt, C. Vocke, N. Wentzensen, R. Worrell, H. Yang, M. Moncrieff, C. Goparaju, J. Melamed, H. Pass, N. Botnariuc, I. Caraman, M. Cernat, I. Chemencedji, A. Clipca, S. Doruc, G. Gorincioi, S. Mura, M. Pirtac, I. Stancul, D. Tcaciuc, M. Albert, I. Alexopoulou, A. Arnaout, J. Bartlett, J. Engel, S. Gilbert, J. Parfitt, H. Sekhon, G. Thomas, D. Rassl, R. Rintoul, C. Bifulco, R. Tamakawa, W. Urba, N. Hayward, H. Timmers, A. Antenucci, F. Facciolo, G. Grazi, M. Marino, R. Merola, R. de Krijger, A. Gimenez-Roqueplo, A. Piché, S. Chevalier, G. McKercher, K. Birsoy, G. Barnett, C. Brewer, C. Farver, T. Naska, N. Pennell, D. Raymond, C. Schilero, K. Smolenski, F. Williams, C. Morrison, J. Borgia, M. Liptay, M. Pool, C. Seder, K. Junker, L. Omberg, M. Dinkin, G. Manikhas, D. Alvaro, M. Bragazzi, V. Cardinale, G. Carpino, E. Gaudio, D. Chesla, S. Cottingham, M. Dubina, F. Moiseenko, R. Dhanasekaran, K. Becker, K. Janssen, J. Slotta-Huspenina, M. Abdel-Rahman, D. Aziz, S. Bell, C. Cebulla, A. Davis, R. Duell, J. Elder, J. Hilty, B. Kumar, J. Lang, N. Lehman, R. Mandt, P. Nguyen, R. Pilarski, K. Rai, L. Schoenfield, K. Senecal, P. Wakely, P. Hansen, R. Lechan, J. Powers, A. Tischler, W. Grizzle, K. Sexton, A. Kastl, J. Henderson, S. Porten, J. Waldmann, M. Fassnacht, S. Asa, D. Schadendorf, M. Couce, M. Graefen, H. Huland, G. Sauter, T. Schlomm, R. Simon, P. Tennstedt, O. Olabode, M. Nelson, O. Bathe, P. Carroll, J. Chan, P. Disaia, P. Glenn, R. Kelley, C. Landen, J. Phillips, M. Prados, J. Simko, K. Smith-McCune, S. VandenBerg, K. Roggin, A. Fehrenbach, A. Kendler, S. Sifri, R. Steele, A. Jimeno, F. Carey, I. Forgie, M. Mannelli, M. Carney, B. Hernandez, B. Campos, C. Herold-Mende, C. Jungk, A. Unterberg, A. von Deimling, A. Bossler, J. Galbraith, L. Jacobus, M. Knudson, T. Knutson, D. Ma, M. Milhem, R. Sigmund, A. Godwin, R. Madan, H. Rosenthal, C. Adebamowo, S. Adebamowo, A. Boussioutas, D. Beer, T. Giordano, A. Mes-Masson, F. Saad, T. Bocklage, L. Landrum, R. Mannel, K. Moore, K. Moxley, R. Postier, J. Walker, R. Zuna, M. Feldman, F. Valdivieso, R. Dhir, J. Luketich, E. Pinero, M. Quintero-Aguilo, C. Carlotti, J. Santos, R. Kemp, A. Sankarankuty, D. Tirapelli, J. Catto, K. Agnew, E. Swisher, J. Creaney, B. Robinson, C. Shelley, E. Godwin, S. Kendall, C. Shipman, C. Bradford, T. Carey, A. Haddad, J. Moyer, L. Peterson, M. Prince, L. Rozek, G. Wolf, R. Bowman, K. Fong, I. Yang, R. Korst, W. Rathmell, J. Fantacone-Campbell, J. Hooke, A. Kovatich, C. Shriver, J. DiPersio, B. Drake, R. Govindan, S. Heath, T. Ley, B. Tine, P. Westervelt, M. Rubin, J. Lee, N. Aredes, and A. Mariamidze. Cell Systems, 6 (3): 271--281.e7 (March 2018)
DOI: 10.1016/j.cels.2018.03.002

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Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection.D. Reiss, I. Avila-Campillo, V. Thorsson, B. Schwikowski, and T. Galitski. BMC Bioinform., (2005)Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic PipelinesK. Ellrott, M. Bailey, G. Saksena, K. Covington, C. Kandoth, C. Stewart, J. Hess, S. Ma, K. Chiotti, M. McLellan and 730 other author(s). Cell Systems, 6 (3): 271--281.e7 (March 2018)Discovery of Regulatory Interactions Through Perturbation: Inference and Experimental DesignT. Ideker, V. Thorsson, and R. Karp. Proceedings of the Pacific Symposium on Biocomputing, World Scientific Press, (2000)A Data Integration Framework for Prediction of Transcription Factor TargetsM. Nykter, H. Lähdesmäki, A. Rust, V. Thorsson, and I. Shmulevich. Annals of the New York Academy of Sciences, (2009)Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics.S. Ramsey, S. Klemm, D. Zak, K. Kennedy, V. Thorsson, B. Li, M. Gilchrist, E. Gold, C. Johnson, V. Litvak and 7 other author(s). PLoS Comput. Biol., (2008)Testing for Differentially-Expressed Genes by Maximum-Likelihood Analysis of Microarray Data.T. Ideker, V. Thorsson, A. Siegel, and L. Hood. J. Comput. Biol., 7 (6): 805-817 (2000)Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 PatientsA. Kahles, K. Lehmann, N. Toussaint, M. Hüser, S. Stark, T. Sachsenberg, O. Stegle, O. Kohlbacher, C. Sander, S. Caesar-Johnson and 725 other author(s). Cancer Cell, 34 (2): 211--224.e6 (August 2018)Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic PipelinesK. Ellrott, M. Bailey, G. Saksena, K. Covington, C. Kandoth, C. Stewart, J. Hess, S. Ma, K. Chiotti, M. McLellan and 730 other author(s). Cell Systems, 6 (3): 271--281.e7 (March 2018)Discovery of Causal Relationships in a Gene-Regulation Pathway from a Mixture of Experimental and Observational DNA Microarray Data.C. Yoo, V. Thorsson, and G. Cooper. Pacific Symposium on Biocomputing, page 498-509. (2002)

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Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

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copydeleteadd this publication to your clipboardcommunity posthistory of this postURLDOIBibTeXEndNoteAPAChicagoDIN 1505HarvardMSOffice XML Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

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Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines