Even the lowest dose of modafinil, an ampakine, improved the wakefulness and cognitive performance of sleep-deprived people; they work in part by boosting glutamate, a key neurotransmitter that facilitates learning & learn and encodes memory.
Eugeroic = “good arousal." Unique class of drugs (adrafinil, modafinil). Like adaptogens (ginseng), only “stimulate when stimulation is required.” Highs and lows associated with other stimulants (amphetamine, etc) are absent with eugeroics.
For narcolepsy, or off-label for depression, night-shift work, ADHD/ADD...a prodrug, metabolizes to modafinil (Provigil®), resulting in nearly identical pharmacological effects, takes 45-60 minutes to reach active levels in bloodstream.
Masters is a leading British pharmaceutical wholesaler and exporter and has been supplying citizens of the USA with medicines since the introduction of the FDA Pilot Scheme of 1988. It complies with all requirements of the Florida Prescription Drug Act...
The AMPA receptor is involved in a process known as long-term potentiation, or LTP – believed to underlie the encoding of many types of memory. In addition to its importance to memory formation, the AMPA receptor plays a central role in “excitatory co
AMPA modulators might ameliorate memory deficits that occur in dementia, such as Alzheimer's disease (AD). However, AMPA receptor mediated excitotoxicity may occur with excessive AMPA receptor activation which occurs in seizures or ischaemia and positive
Modafinil has changed the rules of the game. The drug is what's known as a eugeroic, meaning "good arousal" in Greek. It delivers natural-feeling alertness and wakefulness without the powerful physical and mental jolt that earlier stimulants delivered. "T