%0 Journal Article %1 Patterson2003 %A Patterson, Brian M. %A Danielson, Neil D. %A Lorigan, Gary A. %A Sommer, André J. %D 2003 %J J. Chem. Educ. %K %N 12 %P 1460 %R 10.1021/ed080p1460 %T Analytical Spectroscopy Using Modular Systems %V 80 %X This article describes the development of three analytical spectroscopy experiments that compare the determination of salicylic acid (SA) content in aspirin tablets. The experiments are based on UV–vis, fluorescence, and Raman spectroscopies and utilize modular spectroscopic components. Students assemble their own instruments, optimize them with respect to signal-to-noise, generate calibration curves, determine the SA content in retail aspirin tablets, and assign features in the respective spectra to functional groups within the active material. Using this approach in the discovery-based setting, the students gain invaluable insight into method-specific parameters, such as instrumental components, sample preparation, and analytical capability. In addition, the students learn the fundamentals of fiber optics and signal processing using the low-cost CCD based spectroscopic components.

@article{Patterson2003, abstract = {This article describes the development of three analytical spectroscopy experiments that compare the determination of salicylic acid (SA) content in aspirin tablets. The experiments are based on UV–vis, fluorescence, and Raman spectroscopies and utilize modular spectroscopic components. Students assemble their own instruments, optimize them with respect to signal-to-noise, generate calibration curves, determine the SA content in retail aspirin tablets, and assign features in the respective spectra to functional groups within the active material. Using this approach in the discovery-based setting, the students gain invaluable insight into method-specific parameters, such as instrumental components, sample preparation, and analytical capability. In addition, the students learn the fundamentals of fiber optics and signal processing using the low-cost CCD based spectroscopic components.}, added-at = {2011-09-30T23:14:28.000+0200}, author = {Patterson, Brian M. and Danielson, Neil D. and Lorigan, Gary A. and Sommer, André J.}, biburl = {https://www.bibsonomy.org/bibtex/226b9fe10cdf89f1d37e9a47ad0655594/afcallender}, doi = {10.1021/ed080p1460}, file = {Patterson2003.pdf:indexed\\Patterson2003.pdf:PDF}, groups = {public}, interhash = {1523f6fd5b90922a6dd31b8d3d333b10}, intrahash = {26b9fe10cdf89f1d37e9a47ad0655594}, journal = {J. Chem. Educ.}, keywords = {}, number = 12, pages = 1460, timestamp = {2011-09-30T23:14:28.000+0200}, title = {Analytical Spectroscopy Using Modular Systems}, username = {afcallender}, volume = 80, year = 2003 }