Article,
Lego clocks: building a clock from parts.
Genes & development, 22 (11): 1422--1426 (Jun 1, 2008)
DOI: 10.1101/gad.1686608
Abstract
A new finding opens up speculation that the molecular mechanism of circadian clocks in Synechococcus elongatus is composed of multiple oscillator systems (Kitayama and colleagues, this issue, pp. 1513-1521), as has been described in many eukaryotic clock model systems. However, an alternative intepretation is that the pacemaker mechanism-as previously suggested-lies primarily in the rate of ATP hydrolysis by the clock protein KaiC.
