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A correlative approach for combining microCT, light and transmission electron microscopy in a single 3D scenario

, , , and . (2013)

Abstract

In biomedical research, a huge variety of different techniques is currently available for the structural examination of small specimens, including conventional light microscopy (LM), transmission electron microscopy (TEM), confocal laser scanning microscopy (CLSM), microscopic X-ray computed tomography (microCT), and many others. Since every imaging method is physically limited by certain parameters, a correlative use of complementary methods often yields a significant broader range of information. Here we demonstrate the advantages of the correlative use of microCT, light microscopy, and transmission electron microscopy for the analysis of small biological samples.

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Frontiers in Zoology | Abstract | A correlative approach for combining microCT, light and transmission electron microscopy in a single 3D scenario

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