Aim: Evaluation of effect of shodhana process of datura seed (Datura stramonium) antioxidant activity.
Methods: The datura was purified with two different processes viz. cow’s urine, and cow’s milk by Dolayantra method.
Antioxidant activity was evaluated by in-vitro 1,1-Diphenyl-2-picryl hydrazyl (DPPH) radicals scavenging activity and Ferric reducing power ability (FRPA) assay.
Result: cow urine purified datura (CUD) showed a significant effect in inhibiting DPPH, reaching up to 85.96% at concentration 1000 mcg/ml and its IC50 was 314.3 mcg/ml while Unpurified Datura Seed (UD) reaching up to 86.06% at concentration 1000 mcg/ml and its IC50 was 171.73 mcg/ml. The Cow Milk Purified Datura Seed (CMD) extract reach 69.72% at concentration 1000 mcg/ml and its IC50 value was 640. The IC50 value of Ascorbic acid was 23.35 mcg/ml. CUD showed a significant effect in reduction of ferric ion, reaching up to 85.59% reduction at concentration 1000 mcg/ml and its EC50 was 304.46 mcg/ml while UD reaching up to 86.11% at concentration 1000 mcg/ml and its EC50 was 280.28 mcg/ml. CMD extract reach 52.28% at concentration 1000 mcg/ml and its EC50 value was 1091.3mcg/ml.
%0 Journal Article
%1 umang_haribhai_gajjar_2021_5131622
%A Gajjar, Umang Haribhai
%A Velhal, Niralee Kalpeshkumar
%A Parikh, Hetvi Girdharbhai
%A Parmar, Jayrajsinh Bhartbhai
%A Bhut, Yash
%A Patel, Viral Rupeshbhai
%D 2021
%J World Journal of Biology Pharmacy and Health Sciences
%K Datura Seed
%N 1
%P 030-035
%R 10.30574/wjbphs.2021.7.1.0070
%T Evaluation of antioxidant activity of unpurified and purified datura seed
%U http://wjbphs.com/content/evaluation-antioxidant-activity-unpurified-and-purified-datura-seed
%V 7
%X Aim: Evaluation of effect of shodhana process of datura seed (Datura stramonium) antioxidant activity.
Methods: The datura was purified with two different processes viz. cow’s urine, and cow’s milk by Dolayantra method.
Antioxidant activity was evaluated by in-vitro 1,1-Diphenyl-2-picryl hydrazyl (DPPH) radicals scavenging activity and Ferric reducing power ability (FRPA) assay.
Result: cow urine purified datura (CUD) showed a significant effect in inhibiting DPPH, reaching up to 85.96% at concentration 1000 mcg/ml and its IC50 was 314.3 mcg/ml while Unpurified Datura Seed (UD) reaching up to 86.06% at concentration 1000 mcg/ml and its IC50 was 171.73 mcg/ml. The Cow Milk Purified Datura Seed (CMD) extract reach 69.72% at concentration 1000 mcg/ml and its IC50 value was 640. The IC50 value of Ascorbic acid was 23.35 mcg/ml. CUD showed a significant effect in reduction of ferric ion, reaching up to 85.59% reduction at concentration 1000 mcg/ml and its EC50 was 304.46 mcg/ml while UD reaching up to 86.11% at concentration 1000 mcg/ml and its EC50 was 280.28 mcg/ml. CMD extract reach 52.28% at concentration 1000 mcg/ml and its EC50 value was 1091.3mcg/ml.
@article{umang_haribhai_gajjar_2021_5131622,
abstract = {Aim: Evaluation of effect of shodhana process of datura seed (Datura stramonium) antioxidant activity.
Methods: The datura was purified with two different processes viz. cow’s urine, and cow’s milk by Dolayantra method.
Antioxidant activity was evaluated by in-vitro 1,1-Diphenyl-2-picryl hydrazyl (DPPH) radicals scavenging activity and Ferric reducing power ability (FRPA) assay.
Result: cow urine purified datura (CUD) showed a significant effect in inhibiting DPPH, reaching up to 85.96% at concentration 1000 mcg/ml and its IC50 was 314.3 mcg/ml while Unpurified Datura Seed (UD) reaching up to 86.06% at concentration 1000 mcg/ml and its IC50 was 171.73 mcg/ml. The Cow Milk Purified Datura Seed (CMD) extract reach 69.72% at concentration 1000 mcg/ml and its IC50 value was 640. The IC50 value of Ascorbic acid was 23.35 mcg/ml. CUD showed a significant effect in reduction of ferric ion, reaching up to 85.59% reduction at concentration 1000 mcg/ml and its EC50 was 304.46 mcg/ml while UD reaching up to 86.11% at concentration 1000 mcg/ml and its EC50 was 280.28 mcg/ml. CMD extract reach 52.28% at concentration 1000 mcg/ml and its EC50 value was 1091.3mcg/ml.},
added-at = {2021-07-24T16:14:24.000+0200},
author = {Gajjar, Umang Haribhai and Velhal, Niralee Kalpeshkumar and Parikh, Hetvi Girdharbhai and Parmar, Jayrajsinh Bhartbhai and Bhut, Yash and Patel, Viral Rupeshbhai},
biburl = {https://www.bibsonomy.org/bibtex/26a6ce2654f7940a33c127cf642ee7ca6/wjbphsjournal},
doi = {10.30574/wjbphs.2021.7.1.0070},
interhash = {78f20b125e4165ea2afd5ae305db6ba8},
intrahash = {6a6ce2654f7940a33c127cf642ee7ca6},
issn = {2582-5542},
journal = {{World Journal of Biology Pharmacy and Health Sciences}},
keywords = {Datura Seed},
month = jul,
number = 1,
pages = {030-035},
timestamp = {2021-07-24T16:14:24.000+0200},
title = {Evaluation of antioxidant activity of unpurified and purified datura seed},
url = {http://wjbphs.com/content/evaluation-antioxidant-activity-unpurified-and-purified-datura-seed},
volume = 7,
year = 2021
}