Positive reasons for publishing negative findings.
J. Connor. The American journal of gastroenterology, 103 (9):
2181-3(September 2008)4643<m:linebreak></m:linebreak>JID: 0421030; 0 (Immunosuppressive Agents); 159351-69-6 (everolimus); 53123-88-9 (Sirolimus); CON: Am J Gastroenterol. 2008 Sep;103(9):2284-92. PMID: 18671816; 2008/07/30 aheadofprint; ppublish;<m:linebreak></m:linebreak>Publicació.
DOI: 10.1111/j.1572-0241.2008.02028.x
Abstract
Scientific and medical authors tend to be biased toward submitting "statistically significant" findings for publication. Journals show a similar bias in publishing such "positive" studies. The large number of publications in medical research means that, in a field obsessed with controlling Type I error rates, we have journals with an abundance of Type I errors. Failing to publish studies that do not show a treatment or exposure effect creates a literature conspicuously absent of trials necessary for unbiased meta-analyses and systematic reviews. Furthermore, by shelving or rejecting studies with nonstatistically significant outcomes, authors and editors censor the most important contributors to medical research: our consenting volunteers.
%0 Journal Article
%1 Connor2008
%A Connor, Jason T
%D 2008
%J The American journal of gastroenterology
%K BiomedicalResearch ClinicalTrialsasTopic ClinicalTrialsasTopic:statistics&numericald CrohnDisease CrohnDisease:drugtherapy DataInterpretation Humans ImmunosuppressiveAgents ImmunosuppressiveAgents:therapeuticuse PublicationBias Publishing Publishing:ethics Sirolimus Sirolimus:analogs&derivatives Sirolimus:therapeuticuse Statistical TreatmentFailure
%N 9
%P 2181-3
%R 10.1111/j.1572-0241.2008.02028.x
%T Positive reasons for publishing negative findings.
%U http://www.ncbi.nlm.nih.gov/pubmed/18671812
%V 103
%X Scientific and medical authors tend to be biased toward submitting "statistically significant" findings for publication. Journals show a similar bias in publishing such "positive" studies. The large number of publications in medical research means that, in a field obsessed with controlling Type I error rates, we have journals with an abundance of Type I errors. Failing to publish studies that do not show a treatment or exposure effect creates a literature conspicuously absent of trials necessary for unbiased meta-analyses and systematic reviews. Furthermore, by shelving or rejecting studies with nonstatistically significant outcomes, authors and editors censor the most important contributors to medical research: our consenting volunteers.
%@ 1572-0241
@article{Connor2008,
abstract = {Scientific and medical authors tend to be biased toward submitting "statistically significant" findings for publication. Journals show a similar bias in publishing such "positive" studies. The large number of publications in medical research means that, in a field obsessed with controlling Type I error rates, we have journals with an abundance of Type I errors. Failing to publish studies that do not show a treatment or exposure effect creates a literature conspicuously absent of trials necessary for unbiased meta-analyses and systematic reviews. Furthermore, by shelving or rejecting studies with nonstatistically significant outcomes, authors and editors censor the most important contributors to medical research: our consenting volunteers.},
added-at = {2023-02-03T11:44:35.000+0100},
author = {Connor, Jason T},
biburl = {https://www.bibsonomy.org/bibtex/270f8d20b0fc27a48fab8f6e47c99ebe9/jepcastel},
city = {Berry Consultants, Orlando, Florida 32835, USA.},
doi = {10.1111/j.1572-0241.2008.02028.x},
interhash = {eed6af9716a5a36531750a6b97e250ef},
intrahash = {70f8d20b0fc27a48fab8f6e47c99ebe9},
isbn = {1572-0241},
issn = {1572-0241},
journal = {The American journal of gastroenterology},
keywords = {BiomedicalResearch ClinicalTrialsasTopic ClinicalTrialsasTopic:statistics&numericald CrohnDisease CrohnDisease:drugtherapy DataInterpretation Humans ImmunosuppressiveAgents ImmunosuppressiveAgents:therapeuticuse PublicationBias Publishing Publishing:ethics Sirolimus Sirolimus:analogs&derivatives Sirolimus:therapeuticuse Statistical TreatmentFailure},
month = {9},
note = {4643<m:linebreak></m:linebreak>JID: 0421030; 0 (Immunosuppressive Agents); 159351-69-6 (everolimus); 53123-88-9 (Sirolimus); CON: Am J Gastroenterol. 2008 Sep;103(9):2284-92. PMID: 18671816; 2008/07/30 [aheadofprint]; ppublish;<m:linebreak></m:linebreak>Publicació},
number = 9,
pages = {2181-3},
pmid = {18671812},
timestamp = {2023-02-03T11:44:35.000+0100},
title = {Positive reasons for publishing negative findings.},
url = {http://www.ncbi.nlm.nih.gov/pubmed/18671812},
volume = 103,
year = 2008
}