In the present investigation synthesis of 4-hydroxy-3-methyl-7,8-dihydroquinolin-5(6H)-one was successfully demonstrated from cyclohexane-1,3-dione using microwave heating using proline catalyst. The synthesis of Hexa-Hydro-Quinolone derivatives, carried out by sequential in situ, Michael Addition, Cyclisation, and Aromatization. A new protocol for one step synthesis of 4-hydroxy-3-methyl-7,8-dihydroquinolin-5(6H)-one was successfully demonstrated from cyclohexane-1,3-dione with 98% yield.
%0 Journal Article
%1 sapkal_anjali_2024_11244964
%A Anjali, Sapkal
%A Rakesh, Kumar
%A Abhijeet, Purude
%D 2024
%J World Journal of Biology Pharmacy and Health Sciences
%K Microwave reactions
%N 1
%P 114–116
%R 10.30574/wjbphs.2024.17.1.0018
%T Microwave induced synthesis of 4-hydroxy-3-methyl-7, 8-dihydroquinoline-5(6H)-one using proline catalyst
%U https://wjbphs.com/content/microwave-induced-synthesis-4-hydroxy-3-methyl-7-8-dihydroquinoline-56h-one-using-proline
%V 17
%X In the present investigation synthesis of 4-hydroxy-3-methyl-7,8-dihydroquinolin-5(6H)-one was successfully demonstrated from cyclohexane-1,3-dione using microwave heating using proline catalyst. The synthesis of Hexa-Hydro-Quinolone derivatives, carried out by sequential in situ, Michael Addition, Cyclisation, and Aromatization. A new protocol for one step synthesis of 4-hydroxy-3-methyl-7,8-dihydroquinolin-5(6H)-one was successfully demonstrated from cyclohexane-1,3-dione with 98% yield.
@article{sapkal_anjali_2024_11244964,
abstract = {In the present investigation synthesis of 4-hydroxy-3-methyl-7,8-dihydroquinolin-5(6H)-one was successfully demonstrated from cyclohexane-1,3-dione using microwave heating using proline catalyst. The synthesis of Hexa-Hydro-Quinolone derivatives, carried out by sequential in situ, Michael Addition, Cyclisation, and Aromatization. A new protocol for one step synthesis of 4-hydroxy-3-methyl-7,8-dihydroquinolin-5(6H)-one was successfully demonstrated from cyclohexane-1,3-dione with 98% yield.},
added-at = {2024-05-31T11:03:12.000+0200},
author = {Anjali, Sapkal and Rakesh, Kumar and Abhijeet, Purude},
biburl = {https://www.bibsonomy.org/bibtex/2ab3225861425b96effe35ef11476b051/wjbphsjournal},
doi = {10.30574/wjbphs.2024.17.1.0018},
interhash = {d7d6b8d37fa07d232720a70c8070a1bc},
intrahash = {ab3225861425b96effe35ef11476b051},
issn = {2582-5542},
journal = {{World Journal of Biology Pharmacy and Health Sciences}},
keywords = {Microwave reactions},
month = may,
number = 1,
pages = {114–116},
timestamp = {2024-05-31T11:03:12.000+0200},
title = {Microwave induced synthesis of 4-hydroxy-3-methyl-7, 8-dihydroquinoline-5(6H)-one using proline catalyst},
url = {https://wjbphs.com/content/microwave-induced-synthesis-4-hydroxy-3-methyl-7-8-dihydroquinoline-56h-one-using-proline},
volume = 17,
year = 2024
}