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Comment on "Detecting Novel Associations In Large Data Sets" by Reshef Et Al, Science Dec 16, 2011, and . (2014)cite arxiv:1401.7645Comment: 3 pages, 1 figure.Prediction by supervised principal components, , , and . Journal of the American Statistical Association, 101 (473): 119--137 (2006)Generalized Additive Models, and . Statist. Sci., 1 (3): 297--310 (August 1986)The elements of statistical learning: data mining, inference and prediction, , and . Springer, 2 edition, (2008)Penalized classification using Fisher's linear discriminant, and . Journal of the Royal Statistical Society: Series B (Statistical Methodology), (2011)Repeated observation of breast tumor subtypes in independent gene expression data sets., , , , , , , , , and 6 other author(s). Proc. Natl. Acad. Sci. U.S.A., 100 (14): 8418-23 (2003)Classification by Pairwise Coupling, and . Advances in Neural Information Processing Systems, 10, MIT Press, (1998)Regularization paths and coordinate descent., , and . KDD, page 3. ACM, (2008)Regression shrinkage and selection via the lasso: a retrospective: Regression Shrinkage and Selection via the Lasso. Journal of the Royal Statistical Society: Series B (Statistical Methodology), 73 (3): 273--282 (June 2011)FastCPH: Efficient Survival Analysis for Neural Networks., , , , , , and . CoRR, (2022)