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Genetic and intervention studies implicating complement C3 as a major target for the treatment of periodontitis.

, , , , , , , and . Journal of Immunology, 192 (12): 6020--6027 (June 2014)
DOI: 10.4049/jimmunol.1400569

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Complement inhibition in pre-clinical models of periodontitis and prospects for clinical application., , , , , , and . Seminars in Immunology, 28 (3): 285--291 (June 2016)Genetic and intervention studies implicating complement C3 as a major target for the treatment of periodontitis., , , , , , , and . Journal of Immunology, 192 (12): 6020--6027 (June 2014)Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches., , , , and . Adv.Exp.Med.Biol., (2015)Safety and Efficacy of the Complement Inhibitor AMY-101 in a Natural Model of Periodontitis in Non-human Primates., , , , , , , , , and . Molecular therapy. Methods & clinical development, (September 2017)Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist., , , , , , and . Journal of Immunology, 189 (11): 5442--5448 (December 2012)Inhibition of pre-existing natural periodontitis in non-human primates by a locally administered peptide inhibitor of complement C3., , , , , , , , , and 1 other author(s). J.Clin.Periodontol., 43 (3): 238--249 (March 2016)Role of complement in host-microbe homeostasis of the periodontium., , , , and . 25 (1): 65--72 (February 2013)Neutrophil homeostasis and inflammation: novel paradigms from studying periodontitis., , , and . Journal of leukocyte biology, 98 (4): 539--548 (October 2015)