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Adaptive designs in clinical drug development--an Executive Summary of the PhRMA Working Group.

, , , , , and . Journal of biopharmaceutical statistics, 16 (3): 275-83; discussion 285-91, 293-8, 311-2 (May 2006)5002<br/>LR: 20071115; JID: 9200436; CIN: J Biopharm Stat. 2006 May;16(3):299-309; discussion 311-2. PMID: 16724486; ppublish;<br/>Tipus d'estudis; Dissenys adaptatius.
DOI: 10.1080/10543400600614742

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Adaptive designs in clinical drug development--an Executive Summary of the PhRMA Working Group., , , , , and . Journal of biopharmaceutical statistics, 16 (3): 275-83; discussion 285-91, 293-8, 311-2 (May 2006)5002<br/>LR: 20071115; JID: 9200436; CIN: J Biopharm Stat. 2006 May;16(3):299-309; discussion 311-2. PMID: 16724486; ppublish;<br/>Tipus d'estudis; Dissenys adaptatius.Biopharmaceutical Research, Statistics in.. International Encyclopedia of Statistical Science, Springer, (2011)The role of the minimum clinically important difference and its impact on designing a trial., , , and . Pharmaceutical statistics, 10 (3): 250-6 (2011)6155<m:linebreak></m:linebreak>MDCI; Sample size; Tamaño del efecto.Strong control over multiple endpoints: are we adding value to the assessment of medicines?, and . Pharmaceutical statistics, 12 (4): 189-91 (May 2013)7342<m:linebreak></m:linebreak>JID: 101201192; 2013/01/12 received; 2013/02/13 revised; 2013/04/11 accepted; aheadofprint;<m:linebreak></m:linebreak>Comparacions múltiples.