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Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

A. Antoniou, C. Kartsonaki, O. Sinilnikova, P. Soucy, L. McGuffog, S. Healey, A. Lee, P. Peterlongo, S. Manoukian, B. Peissel, D. Zaffaroni, E. Cattaneo, M. Barile, V. Pensotti, B. Pasini, R. Dolcetti, G. Giannini, A. Putignano, L. Varesco, P. Radice, P. Mai, M. Greene, I. Andrulis, G. Glendon, H. Ozcelik, M. Thomassen, A. Gerdes, T. Kruse, U. Birk Jensen, D. Crüger, M. Caligo, Y. Laitman, R. Milgrom, B. Kaufman, S. Paluch-Shimon, E. Friedman, N. Loman, K. Harbst, A. Lindblom, B. Arver, H. Ehrencrona, B. Melin, K. Nathanson, S. Domchek, T. Rebbeck, A. Jakubowska, J. Lubinski, J. Gronwald, T. Huzarski, T. Byrski, C. Cybulski, B. Gorski, A. Osorio, Ramón y Cajal, Teresa, F. Fostira, R. Andrés, J. Benitez, U. Hamann, F. Hogervorst, M. Rookus, M. Hooning, M. Nelen, van der Luijt, Rob B, van Os, Theo A M, van Asperen, Christi J, P. Devilee, Meijers-Heijboer, Hanne E J, Gómez Garcia, Encarna B, S. Peock, M. Cook, D. Frost, R. Platte, J. Leyland, D. Evans, F. Lalloo, R. Eeles, L. Izatt, J. Adlard, R. Davidson, D. Eccles, K. Ong, J. Cook, F. Douglas, J. Paterson, M. Kennedy, Z. Miedzybrodzka, A. Godwin, D. Stoppa-Lyonnet, B. Buecher, M. Belotti, C. Tirapo, S. Mazoyer, L. Barjhoux, C. Lasset, D. Leroux, L. Faivre, M. Bronner, F. Prieur, C. Nogues, E. Rouleau, P. Pujol, I. Coupier, M. Frénay, J. Hopper, M. Daly, M. Terry, E. John, S. Buys, Y. Yassin, A. Miron, D. Goldgar, C. Singer, M. Tea, G. Pfeiler, A. Dressler, Hansen, Thomas V O, L. Jønson, B. Ejlertsen, R. Barkardottir, T. Kirchhoff, K. Offit, M. Piedmonte, G. Rodriguez, L. Small, J. Boggess, S. Blank, J. Basil, M. Azodi, A. Toland, M. Montagna, S. Tognazzo, S. Agata, E. Imyanitov, R. Janavicius, C. Lazaro, I. Blanco, Pharoah, Paul D P, L. Sucheston, B. Karlan, C. Walsh, E. Olah, A. Bozsik, S. Teo, J. Seldon, M. Beattie, van Rensburg, Elizabeth J, M. Sluiter, O. Diez, R. Schmutzler, B. Wappenschmidt, C. Engel, A. Meindl, I. Ruehl, R. Varon-Mateeva, K. Kast, H. Deissler, D. Niederacher, N. Arnold, D. Gadzicki, I. Schönbuchner, T. Caldes, de la Hoya, Miguel, H. Nevanlinna, K. Aittomäki, M. Dumont, J. Chiquette, M. Tischkowitz, X. Chen, J. Beesley, A. Spurdle, S. Neuhausen, Y. Chun Ding, Z. Fredericksen, X. Wang, V. Pankratz, F. Couch, J. Simard, D. Easton, и G. Chenevix-Trench. Human molecular genetics, 20 (16): 3304–3321 (2011)

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A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general populationA. Antoniou, X. Wang, Z. Fredericksen, L. McGuffog, R. Tarrell, O. Sinilnikova, S. Healey, J. Morrison, C. Kartsonaki, T. Lesnick и 168 other автор(ы). Nature genetics, 42 (10): 885–892 (2010)AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 studyF. Couch, O. Sinilnikova, R. Vierkant, V. Pankratz, Z. Fredericksen, D. Stoppa-Lyonnet, I. Coupier, D. Hughes, A. Hardouin, P. Berthet и 61 other автор(ы). Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16 (7): 1416–1421 (2007)Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriersA. Antoniou, K. Kuchenbaecker, P. Soucy, J. Beesley, X. Chen, L. McGuffog, A. Lee, D. Barrowdale, S. Healey, O. Sinilnikova и 171 other автор(ы). Breast cancer research : BCR, 14 (1): R33 (2012)Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer riskF. Couch, X. Wang, L. McGuffog, A. Lee, C. Olswold, K. Kuchenbaecker, P. Soucy, Z. Fredericksen, D. Barrowdale, J. Dennis и 252 other автор(ы). PLoS genetics, 9 (3): e1003212 (2013)RAD51 135G--C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studiesA. Antoniou, O. Sinilnikova, J. Simard, M. Léoné, M. Dumont, S. Neuhausen, J. Struewing, D. Stoppa-Lyonnet, L. Barjhoux, D. Hughes и 69 other автор(ы). American journal of human genetics, 81 (6): 1186–1200 (2007)Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancerS. Bojesen, K. Pooley, S. Johnatty, J. Beesley, K. Michailidou, J. Tyrer, S. Edwards, H. Pickett, H. Shen, C. Smart и 427 other автор(ы). Nature genetics, 45 (4): 371-84, 384e1-2 (2013)Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriersF. Couch, M. Gaudet, A. Antoniou, S. Ramus, K. Kuchenbaecker, P. Soucy, J. Beesley, X. Chen, X. Wang, T. Kirchhoff и 180 other автор(ы). Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 21 (4): 645–657 (2012)Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriersS. Ramus, A. Antoniou, K. Kuchenbaecker, P. Soucy, J. Beesley, X. Chen, L. McGuffog, O. Sinilnikova, S. Healey, D. Barrowdale и 176 other автор(ы). Human mutation, 33 (4): 690–702 (2012)Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk predictionA. Antoniou, J. Beesley, L. McGuffog, O. Sinilnikova, S. Healey, S. Neuhausen, Y. Ding, T. Rebbeck, J. Weitzel, H. Lynch и 168 other автор(ы). Cancer research, 70 (23): 9742–9754 (2010)Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancersJ. French, M. Ghoussaini, S. Edwards, K. Meyer, K. Michailidou, S. Ahmed, S. Khan, M. Maranian, M. O'Reilly, K. Hillman и 201 other автор(ы). American journal of human genetics, 92 (4): 489–503 (2013)

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