Major depression is a common illness that severely limits psychosocial functioning and diminishes quality of life. In 2008, WHO ranked major depression as the third cause of burden of disease worldwide and projected that the disease will rank first by 2030.1 In practice, its detection, diagnosis, and management often pose challenges for clinicians because of its various presentations, unpredictable course and prognosis, and variable response to treatment.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Open access. Anxiety disorders and self-reported symptoms are highly prevalent in pregnancy. Despite their negative impact on maternal and child outcomes, uncertainty remains regarding which symptoms can be considered accurate indicators of antenatal anxiety. Aims:To examine and synthesise the evidence in relation to the psychometric properties and content of self-report scales used to detect anxiety symptoms in pregnant women.
Anxiety symptoms are common in old age and have been suggested as risk factors for development of cognitive impairment and mortality. The objective of the present study was to investigate whether anxiety symptoms among older adults with a mental health diagnosis are persistent and severity of anxiety predicts cognitive decline and mortality.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Hundreds of genes have been newly linked to depression, shedding light on the origins of the condition and highlighting personality types that could be at risk.
The international study, involving more than two million people, is the largest of its kind. It could inform treatments for the condition, which affects one in five people in the UK and is the leading cause of disability worldwide.
Editorial. There are a number of efficacious pharmacological and non-pharmacological interventions for depressive disorder.3 Antidepressant drugs are recommended and frequently used as first-line therapy for adults with moderate to severe depressive disorder, and in the UK, about 80% of people in primary care receive an antidepressant prescription in the first year of diagnosis.4 However, a significant proportion of these prescriptions are for less than 30 days, while an adequate trial of antidepressants is generally recommended to be 6–8 weeks before changing or stopping the medication.3 A too short duration of treatment limits both the therapeutic effect 5 6 and increases the risk of withdrawal symptoms.
A number of factors contribute to the suboptimal treatment duration of antidepressant drugs, and the two most recognised contributing factors include the …... To read the full article, log in using your NHS OpenAthens details.
Commentary on: Osler M, Rozing MP, Christensen GT, et al. Electroconvulsive therapy and risk of dementia in patients with affective disorders: a cohort study. Lancet Psychiatry 2018;5:348–56.. To read the full article, log in using your NHS OpenAthens details.
Open access. Major Depressive Disorder (MDD) is the leading cause of disability worldwide. The cardinal features of MDD are depressed mood and anhedonia. Anhedonia is defined as a “markedly diminished interest or pleasure in all, or almost all, activities of the day”, and has generally been investigated on group-level using retrospective data (e.g. via questionnaire/interview). However, inferences based on group-level findings not necessarily generalize to daily life experiences within individuals.
Anxiety disorders are common, can result in lifelong suffering, and frequently begin before adolescence. Evidence from adults suggests that altered prefrontal-limbic connectivity is a pathophysiological feature of anxiety disorders. More specifically, in adults with anxiety disorders, decreased fractional anisotropy (FA), a measure of white matter integrity, has been observed in the uncinate fasciculus, the major tract that connects limbic and prefrontal regions. Because of the early onset of anxiety disorders and the increased incidence in anxiety disorders in females during their reproductive years, it is important to understand whether the reduction in uncinate fasciculus FA exists in children with anxiety disorders and the extent to which this alteration is sex related. To address these issues, the authors assessed FA in the uncinate fasciculus in unmedicated boys and girls with anxiety disorders.. Login at top right hand side of page using your MPFT NHS OpenAthens for full text.
This statistical release makes available the most recent Improving Access to Psychological Therapies (IAPT) monthly and quarterly data, including activity, waiting times, and outcomes such as recovery. It also makes available, for the first time, additional experimental statistics about a pilot programme for integrated IAPT services.
Psychology of Violence Vol. 9, Iss. 1, (Jan 2019): 1-17. DOI:10.1037/vio0000156
Objectives: This meta-analysis aimed to explore the relationship between mental health disorders and symptoms of mental health disorders (depression, anxiety, posttraumatic stress disorder [PTSD], antisocial personality disorder [PD], and borderline PD) and physical intimate partner violence (IPV) perpetration and victimization for males and females. To read the full article, log in using your NHS OpenAthens details.
Psychological Medicine; Cambridge Vol. 49, Iss. 3, (Feb 2019): 465. DOI:10.1017/S0033291718001083
Although equally efficacious in the acute phase, it is not known how cognitive therapy (CT) and interpersonal psychotherapy (IPT) for major depressive disorder (MDD) compare in the long run. This study examined the long-term outcomes of CT v. IPT for MDD.. To read the full article, log in using your NHS OpenAthens details.
High levels of physical activity are linked to reduced risk of depression. The question is whether exercise has a direct protective effect or if the link simply reflects the fact that depressed people are less inclined to exert themselves. A mendelian randomisation study using a genetic instrumental variable derived from genome wide association studies and a measure of individual activity obtained from accelerometer recordings suggests that the relation is causal and that exercise does reduce risk of depressive illness. To read the full article, log in using your NHS OpenAthens details.
Open access. There is emerging evidence for the effectiveness of psychodynamic psychotherapy for depressive disorders. However, we know less of how this relation-focused therapy mode is experienced and what the patients themselves identify as helpful. Hence, the purpose of this study is to explore adolescents’ experiences of factors promoting improvement in psychodynamic therapy.
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Implications for research and practice:
> Active pain treatment improves sleep in people with dementia and depression.
> This study paves the way for improved methods; these results should be used as the basis for further exploration of this important issue.
> Future studies should include subjective evaluation of the benefits of pain treatment on sleep and explore improvements in related areas such as day-time functioning and falls. To read the full article, log in using your NHS OpenAthens details
Open access. Depression, which is common following acquired brain injury (ABI), has been shown to predict cognitive impairment, rehabilitation outcome, and quality of life. Whilst many studies have examined links between depression and cognitive–affective processing in the non‐ABI population, their applicability to this important clinical group, where cognitive difficulties can be marked, remains unknown. Here, we investigated biases in prospective cognition, which is known to be disrupted in (non‐ABI) depression yet important for well‐being.
No study has gathered evidence from all randomized clinical trials (RCTs) with anti‐inflammatory drugs measuring antidepressant effects including a detailed assessment of side effects and bias.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
To analyze the association of anxiety symptoms with health care use and costs in people aged 85 and older.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Deficits in anticipating pleasure may be an important dimension of anhedonia and functioning in psychiatric disorders, particularly schizophrenia and depression; however, inconsistent findings have limited the conclusions that can be drawn. We conducted the first systemic review and meta‐analysis of the extant literature for research comparing psychiatric groups to healthy control groups on anticipatory pleasure.