tag :: relationship, Receptor cell signal

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2Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein
J. Vilardaga, M. Frank, C. Krasel, C. Dees, R. Nissenson, и M. Lohse. J Biol Chem, 276 (36): 33435-43 (сентября 2001)Vilardaga, J P Frank, M Krasel, C Dees, C Nissenson, R A Lohse, M J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2001 Sep 7;276(36):33435-43. Epub 2001 May 31..
14 лет назад , @pharmawuerz
1
50
AMP/metabolism
Activation
Animals
Arrestin/*metabolism
Arrestins/metabolism
Binding
Binding,
COS
Cell
Chlorides/pharmacology
Competitive
Compounds/pharmacology
Concentration
Conformation
Cyclic
Dose-Response
Drug
Enzyme
Factors
GTP-Binding
Histidine/chemistry
Hormone,
Hormone/*metabolism
Immunoblotting
Inhibitory
Inositol
Ions/metabolism
Kinases/*metabolism
Kinetics
Ligands
Membrane/metabolism
Mutation
Parathyroid
Phosphates/metabolism
Phosphorylation
Protein
Protein-Serine-Threonine
Relationship,
Signal
Sites
Time
Transduction
Type
Zinc
Zinc/metabolism
Receptor
Proteins/metabolism
150AMP/metabolismActivationAnimalsArrestin/*metabolismArrestins/metabolismBindingBinding,COSCellChlorides/pharmacologyCompetitiveCompounds/pharmacologyConcentrationConformationCyclicDose-ResponseDrugEnzymeFactorsGTP-BindingHistidine/chemistryHormone,Hormone/*metabolismImmunoblottingInhibitoryInositolIons/metabolismKinases/*metabolismKineticsLigandsMembrane/metabolismMutationParathyroidPhosphates/metabolismPhosphorylationProteinProtein-Serine-ThreonineRelationship,SignalSitesTimeTransductionTypeZincZinc/metabolismReceptorProteins/metabolism
(0)
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2Agonist-induced internalization and recycling of the human A(3) adenosine receptors: role in receptor desensitization and resensitization
M. Trincavelli, D. Tuscano, P. Cecchetti, A. Falleni, L. Benzi, K. Klotz, V. Gremigni, F. Cattabeni, A. Lucacchini, и C. Martini. J Neurochem, 75 (4): 1493-501 (октября 2000)Trincavelli, M L Tuscano, D Cecchetti, P Falleni, A Benzi, L Klotz, K N Gremigni, V Cattabeni, F Lucacchini, A Martini, C Research Support, Non-U.S. Gov't United states Journal of neurochemistry J Neurochem. 2000 Oct;75(4):1493-501..
14 лет назад , @pharmawuerz
&
A/pharmacology
A3
Adenosine
Adenosine/*analogs
Affinity
Animals
Assay
Binding,
CHO
Cell
Competitive/drug
Concanavalin
Concentration
Cricetinae
Dose-Response
Drug
Endocytosis/drug
Humans
Hydrogen-Ion
Hypertonic
Immunohistochemistry
Iodine
Labels/pharmacokinetics
Ligands
Membrane/metabolism
P1/*agonists/genetics/*metabolism
Potassium/metabolism
Purinergic
Radioisotopes/analysis
Radioligand
Relationship,
Signal
Solutions/pharmacology
Temperature
Transduction/drug
Transfection
derivatives/pharmacokinetics
effects
effects/*physiology
effects/genetics
Receptor
&A/pharmacologyA3AdenosineAdenosine/*analogsAffinityAnimalsAssayBinding,CHOCellCompetitive/drugConcanavalinConcentrationCricetinaeDose-ResponseDrugEndocytosis/drugHumansHydrogen-IonHypertonicImmunohistochemistryIodineLabels/pharmacokineticsLigandsMembrane/metabolismP1/*agonists/genetics/*metabolismPotassium/metabolismPurinergicRadioisotopes/analysisRadioligandRelationship,SignalSolutions/pharmacologyTemperatureTransduction/drugTransfectionderivatives/pharmacokineticseffectseffects/*physiologyeffects/geneticsReceptor
(0)
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1Crosstalk between Galpha(i)- and Galpha(q)-coupled receptors is mediated by Gbetagamma exchange
U. Quitterer, и M. Lohse. Proc Natl Acad Sci U S A, 96 (19): 10626-31 (сентября 1999)Quitterer, U Lohse, M J United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10626-31..
14 лет назад , @pharmawuerz
Animals
B2
Biological
Bradykinin
Bradykinin/*metabolism
C
COS
Calcium/metabolism
Cross-Talk/*physiology
Dose-Response
Drug
Factors
Fusion
GTP-Binding
Immunoblotting
Inositol
Models,
Mutagenesis
Phosphates/metabolism
Phospholipases/metabolism
Proteins/metabolism
Receptor
Recombinant
Relationship,
Signal
Time
Transduction
Transfection
Triphosphate/metabolism
Type
Uridine
beta-2/metabolism
Cell
Adrenergic
AnimalsB2BiologicalBradykininBradykinin/*metabolismCCOSCalcium/metabolismCross-Talk/*physiologyDose-ResponseDrugFactorsFusionGTP-BindingImmunoblottingInositolModels,MutagenesisPhosphates/metabolismPhospholipases/metabolismProteins/metabolismReceptorRecombinantRelationship,SignalTimeTransductionTransfectionTriphosphate/metabolismTypeUridinebeta-2/metabolismCellAdrenergic
(0)
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2Activation and deactivation kinetics of alpha 2A- and alpha 2C-adrenergic receptor-activated G protein-activated inwardly rectifying K+ channel currents
M. Bunemann, M. Bucheler, M. Philipp, M. Lohse, и L. Hein. J Biol Chem, 276 (50): 47512-7 (декабря 2001)Bunemann, M Bucheler, M M Philipp, M Lohse, M J Hein, L Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2001 Dec 14;276(50):47512-7. Epub 2001 Oct 8..
14 лет назад , @pharmawuerz
*Potassium
Action
Activation
Animals
Assay
Binding
Calcium
Cell
Channels
Channels,
Channels/*chemistry/metabolism
Channels/metabolism
Dose-Response
Drug
Electrophysiology
Enzyme
Factors
Fluorescence
G
GTP-Binding
Humans
Inwardly
Inwardly-Rectifying
Kinetics
Knockout
Line
Mice
Microscopy,
Norepinephrine/metabolism/pharmacology
Potassium
Potentials
Protein
Protein-Coupled
Proteins/metabolism
Radioligand
Rectifying
Relationship,
Signal
Time
Transduction
Transfection
alpha-2/*chemistry/*metabolism
alpha/metabolism
Receptor
Adrenergic
*PotassiumActionActivationAnimalsAssayBindingCalciumCellChannelsChannels,Channels/*chemistry/metabolismChannels/metabolismDose-ResponseDrugElectrophysiologyEnzymeFactorsFluorescenceGGTP-BindingHumansInwardlyInwardly-RectifyingKineticsKnockoutLineMiceMicroscopy,Norepinephrine/metabolism/pharmacologyPotassiumPotentialsProteinProtein-CoupledProteins/metabolismRadioligandRectifyingRelationship,SignalTimeTransductionTransfectionalpha-2/*chemistry/*metabolismalpha/metabolismReceptorAdrenergic
(0)
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1Dantrolene inhibition of ryanodine receptor Ca$^2+$ release channels. Molecular mechanism and isoform selectivity.
F. Zhao, P. Li, S. Chen, C. Louis, и B. Fruen. J. Biol. Chem., 276 (17): 13810--13816 (апреля 2001)
16 лет назад , @hake
11278295
50,
Acid,
Adenine,
Adenosine
Alanine,
Animals,
Arginine,
Binding
Binding,
Caffeine,
Calcium
Calcium,
Cell
Central
Central,
Channel
Channel,
Chloride,
Cloning,
Co,
Complementary,
Concentration
Conformation,
Cryoelectron
Cysteine,
DNA,
Dantrolene,
Dominant,
Dose-Response
Drug,
Electrophysiology,
Fusion
Gating,
Genes,
Gl,
Glutamic
Glutathione
Gov't,
Heart,
Humans,
Inhibitory
Ion
Isoforms,
Kinetics,
Line,
Magnesium
Magnesium,
Mice,
Microscopy,
Molecular,
Muscle
Muscle,
Mutation,
Myocardium,
Nervous
Non-U.S.
P.H.S.,
Point
Protein
Proteins,
Receptor
Recombinant
Relationship,
Relaxants,
Release
Research
Reticulum,
Ryanodine
Ryanodine,
Sarcoplasmic
Signal
Sites,
Skeletal,
Stimulants,
Strontium,
Support,
Swine,
System
Transduction,
Transfection,
Transferase,
Triphosphate,
U.S.
ntraction,
utamic
1127829550,Acid,Adenine,AdenosineAlanine,Animals,Arginine,BindingBinding,Caffeine,CalciumCalcium,CellCentralCentral,ChannelChannel,Chloride,Cloning,Co,Complementary,ConcentrationConformation,CryoelectronCysteine,DNA,Dantrolene,Dominant,Dose-ResponseDrug,Electrophysiology,FusionGating,Genes,Gl,GlutamicGlutathioneGov't,Heart,Humans,InhibitoryIonIsoforms,Kinetics,Line,MagnesiumMagnesium,Mice,Microscopy,Molecular,MuscleMuscle,Mutation,Myocardium,NervousNon-U.S.P.H.S.,PointProteinProteins,ReceptorRecombinantRelationship,Relaxants,ReleaseResearchReticulum,RyanodineRyanodine,SarcoplasmicSignalSites,Skeletal,Stimulants,Strontium,Support,Swine,SystemTransduction,Transfection,Transferase,Triphosphate,U.S.ntraction,utamic
(0)
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1A simplified local control model of calcium-induced calcium release in cardiac ventricular myocytes.
R. Hinch, J. Greenstein, A. Tanskanen, L. Xu, и R. Winslow. Biophys. J., 87 (6): 3723--3736 (декабря 2004)
16 лет назад , @hake
AMP-Dependent
Acid
Action
Adaptor
Adrenergic,
Algorithms,
Amino
Animals,
Biological,
Biophysics,
Calcium
Calcium,
Cardiac,
Cardiovascular,
Cell
Cells,
Chains,
Channel
Channel,
Channels,
Comparative
Complexes,
Computer
Conduction
Contraction,
Cyclic
Dependent
Dogs,
Electrophysiology,
Expression
Extramural,
Factors,
Gating,
Gene
Gov't,
Guinea
Heart
Humans,
Interaction
Ion
Ions,
Isoproterenol,
Kinase,
Kinases,
L-Type,
Long
Mapping,
Markov
Membrane
Membrane,
Models,
Multiprotein
Muscle
Myocardial
Myocardium,
Myocytes,
N.I.H.,
Neurons,
Non-U.S.
P.H.S.,
Phosphatase,
Phosphoprotein
Phosphorylation,
Pigs,
Post-Translational,
Potassium
Potentials,
Processes,
Processing,
Profiling,
Protein
Proteins,
Proteome,
Proteomics,
QT
Receptor
Receptors,
Regulation,
Relationship,
Release
Research
Ryanodine
Ryanodine,
Signal
Signaling,
Simulation,
Stochastic
Structure-Activity
Study,
Substitution,
Support,
Syndrome,
System,
Time
Transducing,
Transduction,
U.S.
Ventricles,
Voltage-Gated,
beta-1,
{C}a$^{2+}$-Calmodulin
AMP-DependentAcidActionAdaptorAdrenergic,Algorithms,AminoAnimals,Biological,Biophysics,CalciumCalcium,Cardiac,Cardiovascular,CellCells,Chains,ChannelChannel,Channels,ComparativeComplexes,ComputerConductionContraction,CyclicDependentDogs,Electrophysiology,ExpressionExtramural,Factors,Gating,GeneGov't,GuineaHeartHumans,InteractionIonIons,Isoproterenol,Kinase,Kinases,L-Type,LongMapping,MarkovMembraneMembrane,Models,MultiproteinMuscleMyocardialMyocardium,Myocytes,N.I.H.,Neurons,Non-U.S.P.H.S.,Phosphatase,PhosphoproteinPhosphorylation,Pigs,Post-Translational,PotassiumPotentials,Processes,Processing,Profiling,ProteinProteins,Proteome,Proteomics,QTReceptorReceptors,Regulation,Relationship,ReleaseResearchRyanodineRyanodine,SignalSignaling,Simulation,StochasticStructure-ActivityStudy,Substitution,Support,Syndrome,System,TimeTransducing,Transduction,U.S.Ventricles,Voltage-Gated,beta-1,{C}a$^{2+}$-Calmodulin
(0)
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1An integrative model of the cardiac ventricular myocyte incorporating local control of Ca$^2+$ release.
J. Greenstein, и R. Winslow. Biophys. J., 83 (6): 2918--2945 (декабря 2002)
16 лет назад , @hake
AMP-Dependent
Acid
Action
Adaptor
Adrenergic,
Algorithms,
Amino
Animals,
Biological,
Biophysics,
Calcium
Calcium,
Cardiac,
Cardiovascular,
Cell
Cells,
Chains,
Channel
Channel,
Channels,
Comparative
Complexes,
Computer
Conduction
Contraction,
Cyclic
Dependent
Dogs,
Electrophysiology,
Expression
Extramural,
Gating,
Gene
Gov't,
Guinea
Heart
Humans,
Interaction
Ion
Ions,
Isoproterenol,
Kinase,
Kinases,
L-Type,
Long
Mapping,
Markov
Membrane
Membrane,
Models,
Multiprotein
Muscle
Myocardial
Myocardium,
Myocytes,
N.I.H.,
Neurons,
Non-U.S.
P.H.S.,
Patch-Clamp
Phosphatase,
Phosphoprotein
Phosphorylation,
Pigs,
Post-Translational,
Potassium
Potentials,
Processes,
Processing,
Profiling,
Protein
Proteins,
Proteome,
Proteomics,
QT
Receptor
Receptors,
Regulation,
Relationship,
Release
Research
Reticulum,
Ryanodine
Ryanodine,
Sarcoplasmic
Signal
Signaling,
Simulation,
Stochastic
Structure-Activity
Study,
Substitution,
Support,
Syndrome,
System,
Techniques,
Time
Transducing,
Transduction,
Ventricles,
{C}a$^{2+}$-Calmodulin
AMP-DependentAcidActionAdaptorAdrenergic,Algorithms,AminoAnimals,Biological,Biophysics,CalciumCalcium,Cardiac,Cardiovascular,CellCells,Chains,ChannelChannel,Channels,ComparativeComplexes,ComputerConductionContraction,CyclicDependentDogs,Electrophysiology,ExpressionExtramural,Gating,GeneGov't,GuineaHeartHumans,InteractionIonIons,Isoproterenol,Kinase,Kinases,L-Type,LongMapping,MarkovMembraneMembrane,Models,MultiproteinMuscleMyocardialMyocardium,Myocytes,N.I.H.,Neurons,Non-U.S.P.H.S.,Patch-ClampPhosphatase,PhosphoproteinPhosphorylation,Pigs,Post-Translational,PotassiumPotentials,Processes,Processing,Profiling,ProteinProteins,Proteome,Proteomics,QTReceptorReceptors,Regulation,Relationship,ReleaseResearchReticulum,RyanodineRyanodine,SarcoplasmicSignalSignaling,Simulation,StochasticStructure-ActivityStudy,Substitution,Support,Syndrome,System,Techniques,TimeTransducing,Transduction,Ventricles,{C}a$^{2+}$-Calmodulin
(0)
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1Modeling the actions of beta-adrenergic signaling on excitation--contraction coupling processes.
J. Greenstein, A. Tanskanen, и R. Winslow. Ann. N. Y. Acad. Sci., (мая 2004)
16 лет назад , @hake
AMP-Dependent
Acid
Action
Adaptor
Adrenergic,
Algorithms,
Amino
Animals,
Biological,
Biophysics,
Calcium
Calcium,
Cardiac,
Cardiovascular,
Cell
Cells,
Chains,
Channel
Channel,
Channels,
Comparative
Complexes,
Computer
Conduction
Contraction,
Cyclic
Dependent
Dogs,
Electrophysiology,
Expression
Extramural,
Factors,
Gating,
Gene
Gov't,
Guinea
Heart
Humans,
Interaction
Ion
Ions,
Isoproterenol,
Kinase,
Kinases,
L-Type,
Long
Mapping,
Markov
Membrane
Membrane,
Models,
Multiprotein
Muscle
Myocardial
Myocardium,
Myocytes,
N.I.H.,
Neurons,
Non-U.S.
P.H.S.,
Phosphatase,
Phosphoprotein
Phosphorylation,
Pigs,
Post-Translational,
Potassium
Potentials,
Processes,
Processing,
Profiling,
Protein
Proteins,
Proteome,
Proteomics,
QT
Receptor
Receptors,
Regulation,
Relationship,
Release
Research
Ryanodine
Ryanodine,
Signal
Signaling,
Simulation,
Stochastic
Structure-Activity
Study,
Substitution,
Support,
Syndrome,
System,
Time
Transducing,
Transduction,
U.S.
Ventricles,
Voltage-Gated,
beta,
{C}a$^{2+}$-Calmodulin
AMP-DependentAcidActionAdaptorAdrenergic,Algorithms,AminoAnimals,Biological,Biophysics,CalciumCalcium,Cardiac,Cardiovascular,CellCells,Chains,ChannelChannel,Channels,ComparativeComplexes,ComputerConductionContraction,CyclicDependentDogs,Electrophysiology,ExpressionExtramural,Factors,Gating,GeneGov't,GuineaHeartHumans,InteractionIonIons,Isoproterenol,Kinase,Kinases,L-Type,LongMapping,MarkovMembraneMembrane,Models,MultiproteinMuscleMyocardialMyocardium,Myocytes,N.I.H.,Neurons,Non-U.S.P.H.S.,Phosphatase,PhosphoproteinPhosphorylation,Pigs,Post-Translational,PotassiumPotentials,Processes,Processing,Profiling,ProteinProteins,Proteome,Proteomics,QTReceptorReceptors,Regulation,Relationship,ReleaseResearchRyanodineRyanodine,SignalSignaling,Simulation,StochasticStructure-ActivityStudy,Substitution,Support,Syndrome,System,TimeTransducing,Transduction,U.S.Ventricles,Voltage-Gated,beta,{C}a$^{2+}$-Calmodulin
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2Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein

2Agonist-induced internalization and recycling of the human A(3) adenosine receptors: role in receptor desensitization and resensitization

1Crosstalk between Galpha(i)- and Galpha(q)-coupled receptors is mediated by Gbetagamma exchange

2Activation and deactivation kinetics of alpha 2A- and alpha 2C-adrenergic receptor-activated G protein-activated inwardly rectifying K+ channel currents

1Dantrolene inhibition of ryanodine receptor Ca$^2+$ release channels. Molecular mechanism and isoform selectivity.

1A simplified local control model of calcium-induced calcium release in cardiac ventricular myocytes.

1An integrative model of the cardiac ventricular myocyte incorporating local control of Ca$^2+$ release.

1Modeling the actions of beta-adrenergic signaling on excitation--contraction coupling processes.

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