Even the lowest dose of modafinil, an ampakine, improved the wakefulness and cognitive performance of sleep-deprived people; they work in part by boosting glutamate, a key neurotransmitter that facilitates learning & learn and encodes memory.
Mayo Clinic researchers presented study findings at 06/2007 American Society of Clinical Oncology (ASCO) meeting. Subjects receiving ginseng reported higher vitality, less fatigue, increased emotional/spiritual wellbeing.