Objectives The study sought to describe whether psychotropic medication may have long-term side effects in patients with stroke compared with controls. Open Access Article
Mindfulness-based therapy can benefit people with drug-resistant epilepsy. This article concerns 60 people, each receiving either four bi-weekly sessions of therapy or social support. They were included in randomised controlled trials to assess their quality of life in epilepsy inventory (QOLEI) score level, seizure patterns, mood levels and neurocognitive functions. Login using your SSSFT NHS OpenAthens for full text. SSOTP - request a copy of the article from the library - http://bit.ly/1Xyazai
Physical speech problems are often less of a problem for people with Parkinson’s disease than the cognitive ability to keep up with conversations. To read the full article, log in using your NHS OpenAthens details
Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is one of the major causes of intractable epilepsy. It may require a multidisciplinary treatment approach. Many causative factors, including perinatal hypoxia, trauma and genetic influences, have been suggested. Although autoimmunity against neuronal cells has recently been recognised to play a supportive role in its development, very few researchers or clinicians believe that immunological insults are a major cause of MTLE-HS. To read the full article, log in using your NHS OpenAthens details
Parkinson's disease (PD) presents as a progressive neurological disorder characterised by a number of motor and non-motor features.1 Muscle strength and power are reduced in people with PD compared with age-matched individuals.2 Resistance training is beneficial in the general older population3 but has not been rigorously investigated in people with PD. To read the full article, log in using your NHS OpenAthens details
We investigated long-term (to 25 years) seizure prognosis and survival in people with newly diagnosed epilepsy in the community. We explored whether prognosis is different in those with epilepsy (>2 unprovoked seizures) and those with a single seizure at presentation. To read the full article, log in using your NHS OpenAthens details
The Neurological Alliance has launched a new patient experience survey for people living with a neurological condition in England. The survey opened on June 30 2016 and will remain open until September 30, and is open to anyone with a neurological condition living in England.
Cochrane reviews of physiotherapy (PT) and occupational therapy (OT) for Parkinson’s disease found insufficient evidence of effectiveness, but previous trials were methodologically flawed with small sample size and short-term follow-up.
Parkinson's disease (PD) presents as a progressive neurological disorder characterised by a number of motor and non-motor features.1 Muscle strength and power are reduced in people with PD compared with age-matched individuals.2 Resistance training is beneficial in the general older population3 but has not been rigorously investigated in people with PD.
Aim
To identify the effects of resistance training on physical function and balance in people with PD. To read the full article, log in using your NHS OpenAthens details
An evaluation has been undertaken of the pilot project to provide a Parkinson’s Disease Nurse Specialist post for two years funded by Parkinson’s UK. - See more at: http://www.sompar.nhs.uk/latest-news/parkinson-s-community-nurse-project-evaluation/#sthash.Ou572RsQ.dpuf
To investigate the feasibility of a full-scale randomised controlled trial of a picture booklet to improve quality of life for people with epilepsy and learning disabilities. Open Access Article
Although lacosamide reduced seizure frequency in people with intractable partial seizures compared with placebo, there was a concomitant increase in adverse events, particularly at the higher doses, which in some ultimately led to treatment withdrawal.
The quality of life (QoL) of informal caregivers of people with Parkinson's disease (PD) (PwP) can be affected by the caring role. Because of cognitive symptoms and diminished activities of daily living, in addition to the management of motor symptoms, carers of PwP and cognitive impairment may experience increased levels of burden and poorer QoL compared with carers of PwP without cognitive impairment. This study aimed to investigate the impact of cognitive impairment in PD upon QoL of carers. Login using your SSSFT NHS OpenAthens for full text. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
Open access. To examine the baseline prevalence and longitudinal evolution in non-motor symptoms (NMS) in a prospective cohort of, at baseline, patients with de novo Parkinson’s disease (PD) compared with healthy controls (HC).
Blood-brain barrier (BBB) disruption has long been recognised as an important early feature of multiple sclerosis (MS) pathology. Traditionally, this has been seen as a by-product of the myelin-specific immune response. Here, we consider whether vascular changes instead play a central role in disease pathogenesis, rather than representing a secondary effect of neuroinflammation or neurodegeneration. To read the full article, log in using your NHS OpenAthens details.
Open access. Letter. Thank you for this excellent and concise article outlining the complexities involved in neuroleptic malignant syndrome (NMS) in association with atypical antipsychotics.1 It serves as a reminder of how guidelines and diagnostic criteria can, for all their clarity, lead to vexing and imperfect choices.
To describe behavioural and psychiatric outcomes of children within 10 years of convulsive status epilepticus (CSE). . Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
As our knowledge of amyotrophic lateral sclerosis (ALS) increases, the salient question has become: Is ALS a single disease or a group of diseases with a final common pathway? Traditionally, ALS has been defined as a rapidly progressive neurodegenerative disorder that affects the large motor neurons of the brain and spinal cord. It presents with an upper or lower motor neuron pattern of weakness but progresses to include all motor neurons (upper and lower, bulbar, cervical, thoracic, and lumbar). Cognition was thought to be affected in only a small subset of patients with ALS. The primary causation theory was that ALS was the result of a single common exposure or genetic mutation, and the primary pathologic finding was simple motor neuron degeneration. Recent studies on the genetics of ALS have changed this view. . Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
To examine the baseline prevalence and longitudinal evolution in non-motor symptoms (NMS) in a prospective cohort of, at baseline, patients with de novo Parkinson’s disease (PD) compared with healthy controls (HC). . To read the full article, log in using your NHS OpenAthens details.
Anxiety is a common neuropsychiatric symptom in Parkinson’s disease (PD), yet the neural mechanisms have been scarcely investigated. Disturbances in dopaminergic and serotonergic signalling may play a role in its pathophysiology. . To read the full article, log in using your NHS OpenAthens details.