jepcastel > RandomizedControlledTrialsasTopic:ethics

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1Active-control clinical trials to establish equivalence or noninferiority: methodological and statistical concepts linked to quality.
M. Gomberg-Maitland, L. Frison, and J. Halperin. American heart journal, 146 (3): 398-403 (September 2003)3379.
2 years ago by @jepcastel
show all tags
Bias(Epidemiology)
ConfidenceIntervals
GuidelinesasTopic
Probability
RandomizedControlledTrialsasTopic:ethics
ReproducibilityofResults
SampleSize
StatisticsasTopic
TherapeuticEquivalency
RCT
Bias(Epidemiology)ConfidenceIntervalsGuidelinesasTopicProbabilityRandomizedControlledTrialsasTopic:ethicsReproducibilityofResultsSampleSizeStatisticsasTopicTherapeuticEquivalencyRCT
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1Sufficiently important difference: expanding the framework of clinical significance.
B. Barrett, D. Brown, M. Mundt, and R. Brown. Medical decision making : an international journal of the Society for Medical Decision Making, 25 (3): 250-61 (2005)6567<m:linebreak></m:linebreak>LR: 20071115; GR: K23 AT00051-01/AT/NCCAM NIH HHS/United States; GR: M01 RR03186/RR/NCRR NIH HHS/United States; JID: 8109073; CIN: Med Decis Making. 2005 May-Jun;25(3):248-9. PMID: 15951452; CIN: Med Decis Making. 2005 May-Jun;25(3):246-7. PMID: 15951451; ppublish;<m:linebreak></m:linebreak>MDCI.
2 years ago by @jepcastel
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AttitudetoHealth
Benchmarking
Cost-BenefitAnalysis
DecisionSupportTechniques
Evidence-BasedMedicine
Humans
InformedConsent
PainMeasurement
Patient-CenteredCare
PatientSelection
QualityofLife
RandomizedControlledTrialsasTopic:adverseeff
RandomizedControlledTrialsasTopic:economics
RandomizedControlledTrialsasTopic:ethics
ResearchDesign
RiskAssessment
RiskAssessment:economics
TreatmentOutcome
RCT
AttitudetoHealthBenchmarkingCost-BenefitAnalysisDecisionSupportTechniquesEvidence-BasedMedicineHumansInformedConsentPainMeasurementPatient-CenteredCarePatientSelectionQualityofLifeRandomizedControlledTrialsasTopic:adverseeffRandomizedControlledTrialsasTopic:economicsRandomizedControlledTrialsasTopic:ethicsResearchDesignRiskAssessmentRiskAssessment:economicsTreatmentOutcomeRCT
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1Efficient ways exist to obtain the optimal sample size in clinical trials in rare diseases.
J. van der Lee, J. Wesseling, M. Tanck, and M. Offringa. Journal of clinical epidemiology, 61 (4): 324-30 (April 2008)4585<m:linebreak></m:linebreak>PUBM: Print-Electronic; JID: 8801383; RF: 50; 2006/08/29 received; 2007/07/09 revised; 2007/07/12 accepted; 2008/02/21 aheadofprint; ppublish;<m:linebreak></m:linebreak>Tipus d'estudis.
2 years ago by @jepcastel
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Child
Clinical
EpidemiologicResearchDesign
Ethics
Humans
RandomizedControlledTrialsasTopic:ethics
RareDiseases
SampleSize
RCT
ChildClinicalEpidemiologicResearchDesignEthicsHumansRandomizedControlledTrialsasTopic:ethicsRareDiseasesSampleSizeRCT
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1Articulating and responding to uncertainties in clinical research.
B. Djulbegovic. The Journal of medicine and philosophy, 32 (2): 79-98 (2007)7494<m:linebreak></m:linebreak>LR: 20071115; GR: 1 R01 NS044417-01/NS/NINDS NIH HHS/United States; JID: 7610512; ppublish;<m:linebreak></m:linebreak>Intervenció/placebo; Recerca clínica; Ètica;.
2 years ago by @jepcastel
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ClinicalTrialsasTopic
ClinicalTrialsasTopic:ethics
Ethics
Humans
Models
RandomizedControlledTrialsasTopic:ethics
Research
ResearchDesign
Theoretical
TherapeuticHumanExperimentation
TherapeuticHumanExperimentation:ethics
Uncertainty
RCT
ClinicalTrialsasTopicClinicalTrialsasTopic:ethicsEthicsHumansModelsRandomizedControlledTrialsasTopic:ethicsResearchResearchDesignTheoreticalTherapeuticHumanExperimentationTherapeuticHumanExperimentation:ethicsUncertaintyRCT
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1Ethical framework for the use of sham procedures in clinical trials.
S. Horng, and F. Miller. Critical care medicine, 31 (3 Suppl): S126-30 (March 2003)4647<m:linebreak></m:linebreak>LR: 20071115; JID: 0355501; 0 (Placebos); RF: 34; ppublish;<m:linebreak></m:linebreak>Intervenció/placebo.
2 years ago by @jepcastel
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Biomedical
Biomedical:ethics
Ethics
HumanExperimentation
HumanExperimentation:ethics
Humans
Investigational
Investigational:ethics
Operative
Operative:ethics
Placebos
RandomizedControlledTrialsasTopic:ethics
Research
Risk
SurgicalProcedures
TechnologyAssessment
Therapies
UnitedStates
RCT
BiomedicalBiomedical:ethicsEthicsHumanExperimentationHumanExperimentation:ethicsHumansInvestigationalInvestigational:ethicsOperativeOperative:ethicsPlacebosRandomizedControlledTrialsasTopic:ethicsResearchRiskSurgicalProceduresTechnologyAssessmentTherapiesUnitedStatesRCT
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1Non-inferiority randomized trials, an issue between science and ethics: the case of the SYNTAX study.
V. Mantovani, V. Lepore, A. Mira, and E. Berglin. Scandinavian cardiovascular journal : SCJ, 44 (6): 321-4 (December 2010)6316<m:linebreak></m:linebreak>JID: 9708377; 2010/10/07 aheadofprint; ppublish;<m:linebreak></m:linebreak>Tests d'equivalència.
2 years ago by @jepcastel
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Angioplasty
Balloon
Coronary
CoronaryArteryBypass
CoronaryArteryDisease
CoronaryArteryDisease:surgery
CoronaryArteryDisease:therapy
DataInterpretation
EndpointDetermination
Ethics
Europe
Humans
RandomizedControlledTrialsasTopic:ethics
Research
ResearchDesign
Statistical
RCT
AngioplastyBalloonCoronaryCoronaryArteryBypassCoronaryArteryDiseaseCoronaryArteryDisease:surgeryCoronaryArteryDisease:therapyDataInterpretationEndpointDeterminationEthicsEuropeHumansRandomizedControlledTrialsasTopic:ethicsResearchResearchDesignStatisticalRCT
(0)
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1The use of unequal randomisation ratios in clinical trials: a review.
J. Dumville, S. Hahn, J. Miles, and D. Torgerson. Contemporary clinical trials, 27 (1): 1-12 (February 2006)5946<m:linebreak></m:linebreak>LR: 20071115; JID: 101242342; CIN: Contemp Clin Trials. 2006 Apr;27(2):207; author reply 207-8. PMID: 16530021; RF: 71; 2004/09/28 received; 2005/05/05 revised; 2005/08/11 accepted; 2005/10/19 aheadofprint; ppublish;<m:linebreak></m:linebreak>Aleatorització.
2 years ago by @jepcastel
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Humans
RandomAllocation
RandomizedControlledTrialsasTopic:economics
RandomizedControlledTrialsasTopic:ethics
ResearchDesign
SampleSize
RCT
HumansRandomAllocationRandomizedControlledTrialsasTopic:economicsRandomizedControlledTrialsasTopic:ethicsResearchDesignSampleSizeRCT
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1Overcoming barriers to recruitment in health research.
J. Hewison, and A. Haines. BMJ (Clinical research ed.), 333 (7562): 300-2 (August 2006)4637<m:linebreak></m:linebreak>LR: 20081120; JID: 8900488; CIN: BMJ. 2006 Aug 19;333(7564):398. PMID: 16916841; CIN: BMJ. 2006 Aug 19;333(7564):398. PMID: 16916840; RF: 16; OID: NLM: PMC1526952; ppublish;<m:linebreak></m:linebreak>Generalització.
2 years ago by @jepcastel
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BiomedicalResearch
BiomedicalResearch:ethics
BiomedicalResearch:organization&administration
Confidentiality
Confidentiality:ethics
DecisionMaking
InformedConsent
PatientSatisfaction
PatientSelection
PatientSelection:ethics
RandomizedControlledTrialsasTopic:ethics
ResearchSubjects
ResearchSubjects:supply&distribution
RCT
BiomedicalResearchBiomedicalResearch:ethicsBiomedicalResearch:organization&administrationConfidentialityConfidentiality:ethicsDecisionMakingInformedConsentPatientSatisfactionPatientSelectionPatientSelection:ethicsRandomizedControlledTrialsasTopic:ethicsResearchSubjectsResearchSubjects:supply&distributionRCT
(0)
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1Reporting implementation in randomized trials: proposed additions to the consolidated standards of reporting trials statement.
E. Mayo-Wilson. American journal of public health, 97 (4): 630-3 (April 2007)4534<m:linebreak></m:linebreak>LR: 20071115; PUBM: Print-Electronic; JID: 1254074; 2007/02/28 aheadofprint; ppublish;<m:linebreak></m:linebreak>Publicació.
2 years ago by @jepcastel
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GuidelinesasTopic
Humans
MandatoryReporting
RandomizedControlledTrialsasTopic:ethics
RandomizedControlledTrialsasTopic:standards
RandomizedControlledTrialsasTopic:statistics
ResearchDesign
TreatmentOutcome
RCT
GuidelinesasTopicHumansMandatoryReportingRandomizedControlledTrialsasTopic:ethicsRandomizedControlledTrialsasTopic:standardsRandomizedControlledTrialsasTopic:statisticsResearchDesignTreatmentOutcomeRCT
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1Adaptive trials in clinical research: scientific and ethical issues to consider.
R. van der Graaf, K. Roes, and J. van Delden. JAMA : the journal of the American Medical Association, 307 (22): 2379-80 (June 2012)6707<m:linebreak></m:linebreak>Disseny; Dissenys adaptatius; RCT; Ètica.
2 years ago by @jepcastel
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Ethics
Humans
InformedConsent
PatientSelection
RandomizedControlledTrialsasTopic:ethics
ReproducibilityofResults
Research
ResearchDesign
SocialValues
RCT
EthicsHumansInformedConsentPatientSelectionRandomizedControlledTrialsasTopic:ethicsReproducibilityofResultsResearchResearchDesignSocialValuesRCT
(0)
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1Designed delays versus rigorous pragmatic trials: lower carat gold standards can produce relevant drug evaluations.
M. Maclure, B. Carleton, and S. Schneeweiss. Medical care, 45 (10 Supl 2): S44-9 (October 2007)6352<m:linebreak></m:linebreak>GR: AG19463/AG/NIA NIH HHS/United States; JID: 0230027; 0 (Cyclooxygenase 2 Inhibitors); ppublish;<m:linebreak></m:linebreak>CER.
2 years ago by @jepcastel
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BritishColumbia
Cost-BenefitAnalysis
Cyclooxygenase2Inhibitors
Cyclooxygenase2Inhibitors:administration&dosa
Cyclooxygenase2Inhibitors:economics
DecisionMaking
DrugCosts
DrugEvaluation
DrugEvaluation:economics
DrugEvaluation:ethics
DrugEvaluation:methods
Humans
Insurance
InterprofessionalRelations
NationalHealthPrograms
NationalHealthPrograms:economics
NationalHealthPrograms:organization&administr
NationalHealthPrograms:statistics&numericald
NebulizersandVaporizers
NebulizersandVaporizers:economics
Organizational
PharmaceuticalServices
PharmaceuticalServices:economics
PharmaceuticalServices:statistics&numericalda
PolicyMaking
RandomizedControlledTrialsasTopic:economics
RandomizedControlledTrialsasTopic:ethics
ResearchDesign
RCT
BritishColumbiaCost-BenefitAnalysisCyclooxygenase2InhibitorsCyclooxygenase2Inhibitors:administration&dosaCyclooxygenase2Inhibitors:economicsDecisionMakingDrugCostsDrugEvaluationDrugEvaluation:economicsDrugEvaluation:ethicsDrugEvaluation:methodsHumansInsuranceInterprofessionalRelationsNationalHealthProgramsNationalHealthPrograms:economicsNationalHealthPrograms:organization&administrNationalHealthPrograms:statistics&numericaldNebulizersandVaporizersNebulizersandVaporizers:economicsOrganizationalPharmaceuticalServicesPharmaceuticalServices:economicsPharmaceuticalServices:statistics&numericaldaPolicyMakingRandomizedControlledTrialsasTopic:economicsRandomizedControlledTrialsasTopic:ethicsResearchDesignRCT
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1Damage to important clinical trials by over-regulation.
S. Yusuf. Clinical trials (London, England), 7 (6): 622-5 (December 2010)5826<m:linebreak></m:linebreak>JID: 101197451; ppublish;<m:linebreak></m:linebreak> <m:linebreak></m:linebreak>Polítiques de recerca.
2 years ago by @jepcastel
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Ethics
EthicsCommittees
GovernmentRegulation
Humans
RandomizedControlledTrialsasTopic:ethics
RandomizedControlledTrialsasTopic:legislation
RandomizedControlledTrialsasTopic:standards
Research
ResearchSubjects
UnitedStates
RCT
EthicsEthicsCommitteesGovernmentRegulationHumansRandomizedControlledTrialsasTopic:ethicsRandomizedControlledTrialsasTopic:legislationRandomizedControlledTrialsasTopic:standardsResearchResearchSubjectsUnitedStatesRCT
(0)
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1A guide to the design and analysis of small clinical studies.
F. Kianifard, and M. Islam. Pharmaceutical statistics, 10 (4): 363-8 (2011)6089<m:linebreak></m:linebreak>JID: 101201192; aheadofprint;<m:linebreak></m:linebreak>Disseny; Estudi pilot; Estudi petit.
2 years ago by @jepcastel
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Bias(Epidemiology)
ClinicalTrialsasTopic
ClinicalTrialsasTopic:ethics
ClinicalTrialsasTopic:methods
DataInterpretation
DrugIndustry
DrugIndustry:methods
Humans
InstituteofMedicine(U.S.)
Models
RandomizedControlledTrialsasTopic:ethics
ResearchDesign
SampleSize
Statistical
UnitedStates
RCT
Bias(Epidemiology)ClinicalTrialsasTopicClinicalTrialsasTopic:ethicsClinicalTrialsasTopic:methodsDataInterpretationDrugIndustryDrugIndustry:methodsHumansInstituteofMedicine(U.S.)ModelsRandomizedControlledTrialsasTopic:ethicsResearchDesignSampleSizeStatisticalUnitedStatesRCT
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1Early stopping rules in oncology: considerations for clinicians.
S. Mukherjee, J. Goffin, V. Taylor, K. Anderson, and G. Pond. European journal of cancer (Oxford, England : 1990), 47 (16): 2381-6 (November 2011)Comparacions múltiples; Early stopping; RCT; Oncologia.
2 years ago by @jepcastel
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BayesTheorem
ClinicalTrialsDataMonitoringCommittees
DataInterpretation
EarlyTerminationofClinicalTrials
EarlyTerminationofClinicalTrials:methods
EarlyTerminationofClinicalTrials:standards
EarlyTerminationofClinicalTrials:statistics&
Ethics
Humans
Medical
RandomizedControlledTrialsasTopic:ethics
RandomizedControlledTrialsasTopic:statistics
Statistical
RCT
BayesTheoremClinicalTrialsDataMonitoringCommitteesDataInterpretationEarlyTerminationofClinicalTrialsEarlyTerminationofClinicalTrials:methodsEarlyTerminationofClinicalTrials:standardsEarlyTerminationofClinicalTrials:statistics&EthicsHumansMedicalRandomizedControlledTrialsasTopic:ethicsRandomizedControlledTrialsasTopic:statisticsStatisticalRCT
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1Commentary #1: Adaptive randomization.
D. Streiner. Journal of clinical psychopharmacology, 34 (1): 7-8 (March 2014)Aleatorització; Dissenys adaptatius; Introductori.
2 years ago by @jepcastel
show all tags
Evidence-BasedMedicine
Evidence-BasedMedicine:ethics
Humans
RandomAllocation
RandomizedControlledTrialsasTopic:ethics
SampleSize
TreatmentOutcome
RCT
Evidence-BasedMedicineEvidence-BasedMedicine:ethicsHumansRandomAllocationRandomizedControlledTrialsasTopic:ethicsSampleSizeTreatmentOutcomeRCT
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1Active-control clinical trials to establish equivalence or noninferiority: methodological and statistical concepts linked to quality.

1Sufficiently important difference: expanding the framework of clinical significance.

1Efficient ways exist to obtain the optimal sample size in clinical trials in rare diseases.

1Articulating and responding to uncertainties in clinical research.

1Ethical framework for the use of sham procedures in clinical trials.

1Non-inferiority randomized trials, an issue between science and ethics: the case of the SYNTAX study.

1The use of unequal randomisation ratios in clinical trials: a review.

1Overcoming barriers to recruitment in health research.

1Reporting implementation in randomized trials: proposed additions to the consolidated standards of reporting trials statement.

1Adaptive trials in clinical research: scientific and ethical issues to consider.

1Designed delays versus rigorous pragmatic trials: lower carat gold standards can produce relevant drug evaluations.

1Damage to important clinical trials by over-regulation.

1A guide to the design and analysis of small clinical studies.

1Early stopping rules in oncology: considerations for clinicians.

1Commentary #1: Adaptive randomization.

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