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1SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials.
A. Chan, J. Tetzlaff, P. Gøtzsche, D. Altman, H. Mann, J. Berlin, K. Dickersin, A. Hróbjartsson, K. Schulz, W. Parulekar und 3 andere Autor(en). BMJ (Clinical research ed.), (Januar 2013)7139<m:linebreak></m:linebreak>JID: 8900488; OID: NLM: PMC3541470; epublish;<m:linebreak></m:linebreak>Protocol; RCT.
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Checklist
ClinicalProtocols
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ChecklistClinicalProtocolsClinicalProtocols:standardsClinicalTrialsDataMonitoringCommitteesClinicalTrialsasTopicClinicalTrialsasTopic:methodsClinicalTrialsasTopic:standardsClinicalTrialsasTopic:statistics&numericaldComputerSecurityDataCollectionDataCollection:methodsEthicsHumansMedicalMedicalAuditPatientSelectionPracticeGuidelinesasTopicProfessionalRoleQualityControlRandomAllocationResearchDesignResearchPersonnelResearchSupportasTopicSampleSizeSocialResponsibilityStatisticsasTopicTimeFactorsTreatmentOutcome
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1Therapeutic equivalence: concept and evidence levels.
O. Sánchez, F. Latorre, M. Blanco, und P. Bosch. Medicina clínica, 129 (19): 736-45 (November 2007)4388<m:linebreak></m:linebreak>PUBM: Print; JID: 0376377; RF: 69; ppublish;<m:linebreak></m:linebreak>Tests d'equivalència.
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ClinicalMedicine
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ClinicalTrialsasTopic:standards
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1Methodological issues in comparative effectiveness research: clinical trials.
P. Peduzzi, T. Kyriakides, T. O'Connor, P. Guarino, S. Warren, und G. Huang. The American journal of medicine, 123 (12 Suppl 1): e8-15 (Dezember 2010)5918<m:linebreak></m:linebreak>CI: Copyright (c) 2010; JID: 0267200; ppublish;<m:linebreak></m:linebreak>CER.
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1Are we doing any good by doing really well? (Where's the Bacon?).
D. Herbert. Medical physics, 30 (4): 489-94 (April 2003)3511<m:linebreak></m:linebreak>Publicació.
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1A primer on the design, conduct, and interpretation of clinical trials.
L. Appel. Clinical journal of the American Society of Nephrology : CJASN, 1 (6): 1360-7 (November 2006)5015<m:linebreak></m:linebreak>LR: 20071115; JID: 101271570; 2006/10/11 aheadofprint; ppublish;<m:linebreak></m:linebreak>Disseny; Introductori; RCT; Nefrologia.
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ClinicalTrialsasTopic
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ClinicalTrialsasTopicClinicalTrialsasTopic:methodsClinicalTrialsasTopic:standardsFactorAnalysisHumansPatientSelectionRandomizedControlledTrialsasTopic:standardsResearchDesignStatisticalRCT
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1Benefits, challenges and obstacles of adaptive clinical trial designs.
S. Chow, und R. Corey. Orphanet journal of rare diseases, (Januar 2011)6593<m:linebreak></m:linebreak>GR: 2P30 AI064518/AI/NIAID NIH HHS/United States; JID: 101266602; OID: NLM: PMC3248853; 2011/08/22 received; 2011/11/30 accepted; 2011/11/30 aheadofprint; epublish;<m:linebreak></m:linebreak>Tipus d'estudis; Dissenys adaptatius.
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ClinicalTrialsasTopic
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Drug
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ClinicalTrialsasTopicClinicalTrialsasTopic:methodsClinicalTrialsasTopic:standardsDataInterpretationDose-ResponseRelationshipDrugDrugIndustryDrugIndustry:standardsEndpointDeterminationHumansResearchDesignSampleSizeStatisticalTreatmentOutcomeUnitedStatesUnitedStatesFoodandDrugAdministration
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1The unpredictability paradox: review of empirical comparisons of randomised and non-randomised clinical trials.
R. Kunz, und A. Oxman. BMJ (Clinical research ed.), 317 (7167): 1185-90 (Oktober 1998)3994<br/>Tipus d'estudis.
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ClinicalTrialsasTopic
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DataCollection
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ClinicalTrialsasTopicClinicalTrialsasTopic:methodsClinicalTrialsasTopic:standardsDataCollectionQualityControlRandomAllocationRandomizedControlledTrialsasTopic:standardsSelectionBiasRCT
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1Using balance statistics to determine the optimal number of controls in matching studies.
A. Linden, und S. Samuels. Journal of evaluation in clinical practice, 19 (5): 968-75 (Oktober 2013)CI: (c) 2013; JID: 9609066; OTO: NOTNLM; 2013/07/02 accepted; aheadofprint;.
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Bias(Epidemiology)
ClinicalTrialsasTopic
ClinicalTrialsasTopic:methods
ClinicalTrialsasTopic:standards
DataInterpretation
Humans
OutcomeAssessment(HealthCare)
OutcomeAssessment(HealthCare):methods
OutcomeAssessment(HealthCare):statistics&num
ResearchDesign
ResearchDesign:standards
SampleSize
Statistical
TreatmentOutcome
Bias(Epidemiology)ClinicalTrialsasTopicClinicalTrialsasTopic:methodsClinicalTrialsasTopic:standardsDataInterpretationHumansOutcomeAssessment(HealthCare)OutcomeAssessment(HealthCare):methodsOutcomeAssessment(HealthCare):statistics&numResearchDesignResearchDesign:standardsSampleSizeStatisticalTreatmentOutcome
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1From hot hands to declining effects: the risks of small numbers.
M. Lauer. Journal of the American College of Cardiology, 60 (1): 72-4 (Juli 2012)6821<m:linebreak></m:linebreak>CI: Copyright (c) 2012; JID: 8301365; 0 (Angiotensin Receptor Antagonists); 0 (Natriuretic Agents); 114471-18-0 (Natriuretic Peptide, Brain); EC 1.14.14.1 (Aryl Hydrocarbon Hydroxylases); EC 1.14.14.1 (CYP2C19 protein, human); 2012/01/09 received; 2012/02/20 revised; 2012/02/21 accepted; ppublish;<m:linebreak></m:linebreak>Disseny; RCT; Estudi petit; Bias; Exemples; CV.
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AcuteCoronarySyndrome
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RCT
AcuteCoronarySyndromeAcuteCoronarySyndrome:enzymologyAcuteCoronarySyndrome:geneticsAngiotensinReceptorAntagonistsAngiotensinReceptorAntagonists:therapeuticuseArylHydrocarbonHydroxylasesArylHydrocarbonHydroxylases:geneticsBrainBrain:therapeuticuseClinicalTrialsasTopicClinicalTrialsasTopic:methodsClinicalTrialsasTopic:standardsGenotypeHeartFailureHeartFailure:drugtherapyHumansNatriureticAgentsNatriureticAgents:therapeuticuseNatriureticPeptideOutcomeAssessment(HealthCare)ProbabilityProbabilityTheoryPublicationBiasRandomizedControlledTrialsasTopic:standardsSampleSizeRCT
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1Checklist for the qualitative evaluation of clinical studies with particular focus on external validity and model validity.
G. Bornhöft, S. Maxion-Bergemann, U. Wolf, G. Kienle, A. Michalsen, H. Vollmar, S. Gilbertson, und P. Matthiessen. BMC medical research methodology, (Januar 2006)5510<m:linebreak></m:linebreak>LR: 20091118; JID: 100968545; OID: NLM: PMC1764896; 2006/06/27 received; 2006/12/11 accepted; 2006/12/11 aheadofprint; epublish;<m:linebreak></m:linebreak>Critical appraisal; Checklist.
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Bias(Epidemiology)
ClinicalTrialsasTopic
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ClinicalTrialsasTopic:standards
DataInterpretation
EvaluationStudiesasTopic
GuidelinesasTopic
Humans
InformedConsent
PatientSelection
QualityControl
ReferenceStandards
ReproducibilityofResults
ResearchDesign
SelectionBias
Statistical
TreatmentOutcome
Bias(Epidemiology)ClinicalTrialsasTopicClinicalTrialsasTopic:methodsClinicalTrialsasTopic:standardsDataInterpretationEvaluationStudiesasTopicGuidelinesasTopicHumansInformedConsentPatientSelectionQualityControlReferenceStandardsReproducibilityofResultsResearchDesignSelectionBiasStatisticalTreatmentOutcome
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1How to improve the quality of clinical trials.
I. Galende, J. Sacristán, und J. Soto. Medicina clínica, 102 (12): 465-70 (April 1994)7477<m:linebreak></m:linebreak>LR: 20071115; JID: 0376377; ppublish;<m:linebreak></m:linebreak>Disseny; RCT; Introductori.
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Bioethics
ClinicalTrialsasTopic
ClinicalTrialsasTopic:methods
ClinicalTrialsasTopic:standards
DataInterpretation
Humans
RandomAllocation
ResearchDesign
Statistical
BioethicsClinicalTrialsasTopicClinicalTrialsasTopic:methodsClinicalTrialsasTopic:standardsDataInterpretationHumansRandomAllocationResearchDesignStatistical
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1Assessing research results in the medical literature: trust but verify.
R. Califf, J. McCall, und R. Harrington. JAMA internal medicine, 173 (12): 1053-5 (Juni 2013)7351<m:linebreak></m:linebreak>JID: 101589534; aheadofprint; SO: JAMA Intern Med. 2013 Apr 22:1-3. doi: 10.1001/jamainternmed.2013.829.;<m:linebreak></m:linebreak>Recerca clínica; Publicació.
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BiomedicalResearch
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1Adaptive designs in clinical drug development--an Executive Summary of the PhRMA Working Group.
P. Gallo, C. Chuang-Stein, V. Dragalin, B. Gaydos, M. Krams, und J. Pinheiro. Journal of biopharmaceutical statistics, 16 (3): 275-83; discussion 285-91, 293-8, 311-2 (Mai 2006)5002<br/>LR: 20071115; JID: 9200436; CIN: J Biopharm Stat. 2006 May;16(3):299-309; discussion 311-2. PMID: 16724486; ppublish;<br/>Tipus d'estudis; Dissenys adaptatius.
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1Bayesian methodology for the design and interpretation of clinical trials in critical care medicine: a primer for clinicians.
A. Kalil, und J. Sun. Critical care medicine, 42 (10): 2267-77 (Oktober 2014)Mètodes bayessians; RCT; Introductori; UCI.
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BayesTheorem
ClinicalTrials
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ComparativeEffectivenessResearch
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1Statistical Controversies in Reporting of Clinical Trials: Part 2 of a 4-Part Series on Statistics for Clinical Trials.
S. Pocock, J. McMurray, und T. Collier. Journal of the American College of Cardiology, 66 (23): 2648-62 (Dezember 2015)Disseny; RCT; CV; Introductori; Comparacions múltiples; Composite endpoints; Intention to treat; Anàlisi de subgrups.
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Cardiology
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1SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials.

1Therapeutic equivalence: concept and evidence levels.

1Methodological issues in comparative effectiveness research: clinical trials.

1Are we doing any good by doing really well? (Where's the Bacon?).

1A primer on the design, conduct, and interpretation of clinical trials.

1Benefits, challenges and obstacles of adaptive clinical trial designs.

1The unpredictability paradox: review of empirical comparisons of randomised and non-randomised clinical trials.

1Using balance statistics to determine the optimal number of controls in matching studies.

1From hot hands to declining effects: the risks of small numbers.

1Checklist for the qualitative evaluation of clinical studies with particular focus on external validity and model validity.

1How to improve the quality of clinical trials.

1Assessing research results in the medical literature: trust but verify.

1Adaptive designs in clinical drug development--an Executive Summary of the PhRMA Working Group.

1Bayesian methodology for the design and interpretation of clinical trials in critical care medicine: a primer for clinicians.

1Statistical Controversies in Reporting of Clinical Trials: Part 2 of a 4-Part Series on Statistics for Clinical Trials.

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