Ketamine, an N-methyl-d-aspartate glutamate receptor antagonist, has demonstrated a rapid-onset antidepressant effect in patients with treatment-resistant depression. This study evaluated the efficacy of twice- and thrice-weekly intravenous administration of ketamine in sustaining initial antidepressant effects in patients with treatment-resistant depression. Login at top right hand side of page using your SSSFT NHS Athens for full text. SSOTP - request a copy of the article from the library http://bit.ly/1Xyazai
A disturbed circadian rhythm seems to be a causal factor in the occurrence of depressive disorders in patients with Parkinson’s disease (PD). The circadian rhythm can be restored with light. Therefore, Bright Light Therapy (BLT) might be a new treatment option for depression in PD patients.
This review and consensus statement provides a general overview of the data on the use of ketamine for the treatment of mood disorders and highlights the limitations of the existing knowledge. While ketamine may be beneficial to some patients with mood disorders, it is important to consider the limitations of the available data and the potential risk associated with the drug when considering the treatment option. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Open access. People with a family history of major depressive disorder (MDD) or bipolar disorder (BD) report specific psychoeducational needs that are unmet by existing online interventions. This trial aimed to test whether an interactive website for people at familial risk for depression (intervention) would improve intention to adopt, or actual adoption of, depression prevention strategies (primary outcome) and a range of secondary outcome measures.
Impaired ability to recall specific autobiographical memories is characteristic of depression, which when reversed, may have therapeutic benefits. This cluster-randomized controlled pilot trial investigated efficacy and aspects of acceptability, and feasibility of MEmory Specificity Training (MEST) relative to Psychoeducation and Supportive Counselling (PSC) for Major Depressive Disorder (N = 62).. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Depression and anxiety are common, with one in six people experiencing symptoms in any given week. Of these people, 8.32 million are prescribed antidepressants. People living with HIV are likely to experience psychiatric disorder, with one in three experiencing depression and anxiety, and being at greater risk of developing post-traumatic stress disorder... This article seeks to raise awareness of sexual side-effects of psychotropic medications and draw attention to ethical issues related to post selective serotonin reuptake inhibitor sexual dysfunction (PSSD)
To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The authors sought to determine whether symptoms experienced by formerly depressed patients after at least 8 weeks of remission can be used to identify their risk for relapse during the next 6 months. Login using your SSSFT NHS OpenAthens for full text. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
A disturbed sense of self is a core feature of depression. The medial prefrontal cortex, which has a central role in self-appraisal processes, is often implicated in the illness, although it remains unclear how functional alterations of the region contribute to the observed disturbances. The aim of this study was to clarify the role of the medial prefrontal cortex in self-appraisal processes in depression. Login at top right hand side of page using your SSSFT NHS Athens for full text.
Commentary on:
Rentala S, Fong TC, Nattala P, et al. Effectiveness of body-mind-spirit intervention on well-being, functional impairment and quality of life among depressive patients—a randomized controlled trial. J Adv Nurs 2015;71:2153–63.
Implications for practice and research
A body-mind-spirit (BMS) intervention with pharmacotherapy for depression can help patients manage their condition and increase their quality of life and well-being.
Nurses trained to deliver a BMS intervention to patients can play a critical role in providing integrated clinical care in a hospital setting.
Research on this intervention can make use of existing methods to further refine the efficiency and quality of the intervention programme being developed.
To read the full article, log in using your NHS Athens
Accessible summary:
Older people with learning disabilities who develop memory problems are likely to feel sad.
There is much information showing how people with learning disabilities can learn new behaviours which help them to think differently and feel better.
This is the story of how I helped one older man with learning disabilities and memory problems to change how he was behaving and feel happier. Login using your SSSFT NHS Athens for full text. SSOTP - request a copy of the article from the library http://www.sssft.nhs.uk/library
The Treatment-Resistant Depression Registry investigated whether adjunctive vagus nerve stimulation (VNS) with treatment as usual in depression has superior long-term outcomes compared with treatment as usual only. Login at top right hand side of page using your SSSFT NHS Athens for full text. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
There are many effective psychological therapies to help teenagers with depression, anxiety or other mental health problems. Unfortunately, for various reasons, most teenagers never get access to a professional therapist. To overcome this problem, some researchers are exploring the potential of brief, “single-session” interventions that can be delivered cheaply and easily to many at-risk teenagers outside of a clinical context. In The Journal of Child Psychology and Psychiatry, Jessica Schleider and John Weisz at Harvard University present extremely promising results from their trial of a 30-minute computer session teaching depressed and anxious teenagers that personality is malleable.
Psychostimulant augmentation is considered a potential treatment strategy for individuals with major depressive disorder who do not adequately respond to antidepressant monotherapy. The primary objective of this 12-month open-label extension study was to evaluate the safety and tolerability of lisdexamfetamine dimesylate (LDX) as augmentation therapy to an antidepressant in adults with major depressive disorder.. MPFT staff can use the OVID link, or you can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
Blog post about this recent systematic review by Woody et al. (2017) aimed to give an up-to-date summary of the prevalence and incidence of perinatal depression. In their review, Woody et al. also examined factors which might explain the difference in depression prevalence estimates between studies, such as whether the study was conducted during pregnancy or the postnatal period, and where the study was conducted.
A range of free courses to support people who are dealing with anxiety, stress and depression are being offered throughout Herefordshire.
Let’s Talk is an Improving Access to Psychological Therapy (IAPT) service and is part of 2gether NHS Foundation Trust. The courses provide education on topics related to stress, anxiety and depression, and cover practical techniques and tips to help people learn to manage their mood.
The courses run for four to eight weeks, are run by friendly and professional staff, and are open to anyone who wishes to use them. Some courses are only available for people registered with a Herefordshire GP.
Seasonal affective disorder (SAD) is common and debilitating. The standard of care includes light therapy provided by a light box; however, this treatment is restrictive and only moderately effective. Advances in LED technology enable lighting solutions that emit vastly more light than traditional light boxes. Here, we assess the feasibility of BROAD (Bright, whole-ROom, All-Day) light therapy and get a first estimate for its potential effectiveness.
Late-life depressive symptoms have been extensively studied for their relationship with incident dementia, but have been typically assessed at a single timepoint. Such an approach neglects the course of depression, which, given its remitting and relapsing nature, might provide further insights into the complex association of depression with dementia. We therefore repeatedly measured depressive symptoms in a population of adults over a decade to study the subsequent risk of dementia. Please contact the library to receive a copy of this article - http://bit.ly/1Xyazai
A. B, E. CR, F. T, G. FA, K. T, B. G, K. N, und M. S. Cochrane Database of Systematic Reviews, (2009)Art. No.: CD 007954. DOI: 10. 1002 / 14651858. CD 007954.